Harold A. Scheraga
Cornell University
1160 Papers
25.6K Citations
Harold A. Scheraga is an academic researcher from Cornell University. The author has contributed to research in topics: Protein structure & Protein folding. The author has an hindex of 120, co-authored 1152 publications. Previous affiliations of Harold A. Scheraga include University of Gdańsk & National University of San Luis.
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Papers
Interaction of thrombin and fibrinogen and the polymerization of fibrin monomer
TL;DR: The kinetics of the proteolytic action of thrombin on fibrinogen to release fibr inopeptides A and B from the Aa and BB chains, respectively, and the mechanism of formation of the intermediate polymers from the resultingfibrin monomer are studied.
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Preparation and characterization of a fully iodinated insulin derivative.
TL;DR: In the course of a study of the thermodynamics of the ionization of the lysyl residue of insulin (l), it was found desirable to make an iodinated derivative of insulin in order to convert the four tyrosyl residues in the monomer (molecular weight 5733 (2)) to 3,5-diiodotyrosyls groups which have lower pK values as mentioned in this paper.
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Theoretical Modeling of Electrostatic Effects of Titratable Side-Chain Groups on Protein Conformation in a Polar Ionic Solution. 1. Potential of Mean Force between Charged Lysine Residues and Titration of Poly(L-lysine) in 95% Methanol Solution
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Comparison of the low energy conformations of an oncogenic and a non-oncogenic p21 protein, neither of which binds GTP or GDP
Adam Liwo,Kenneth D. Gibson,Harold A. Scheraga,Paul W. Brandt-Rauf,Regina Monaco,Matthew R. Pincus +5 more
TL;DR: The low energy conformations of the two multiply substituted mutant p21 proteins are calculated using a new adaptation of the electrostatically driven Monte Carlo (EDMC) technique, based on the program ECEPP, to explore the conformational space available to both proteins and to compute the average structures for both using statistical mechanical averaging.
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