Harold A. Scheraga
Cornell University
1160 Papers
25.6K Citations
Harold A. Scheraga is an academic researcher from Cornell University. The author has contributed to research in topics: Protein structure & Protein folding. The author has an hindex of 120, co-authored 1152 publications. Previous affiliations of Harold A. Scheraga include University of Gdańsk & National University of San Luis.
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Papers
Regeneration of bovine pancreatic ribonuclease A. 3. Dependence on the nature of the redox reagent.
TL;DR: The regeneration pathways of bovine pancreatic ribonuclease A depend on the nature of the redox reagent as well as theRedox potential at which they are used, while the use of GSSG/GSH favors multiple regeneration pathways, whileThe use of DTTox/DTTred favors regeneration through fewer pathways.
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Reversible blocking of half-cystine residues of proteins and an irreversible specific deamidation of asparagine-67 of S-sulforibonuclease under mild conditions.
TL;DR: Evidence is presented that demonstrates that this additional modification is due to the specific deamidation of asparagine-67 and the significance of this finding for studies of the folding of RNase A is discussed.
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Analysis of the structure of ribonuclease a in native and partially denatured states by time-resolved nonradiative dynamic excitation energy transfer between site-specific extrinsic probes
TL;DR: Time-resolved fluorescence measurements were used to determine the extent of nonradiative excitation energy transfer between donor and acceptor probes, which allowed recovery of parameters describing the distribution of interprobe distances and the diffusion coefficient of the ends of the segments defined by the pairs of sites labeled by the probes.
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