Harold A. Scheraga
Cornell University
1160 Papers
25.6K Citations
Harold A. Scheraga is an academic researcher from Cornell University. The author has contributed to research in topics: Protein structure & Protein folding. The author has an hindex of 120, co-authored 1152 publications. Previous affiliations of Harold A. Scheraga include University of Gdańsk & National University of San Luis.
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Papers
Prediction of the location of structural domains in globular proteins
TL;DR: The technique presented here also permits the prediction of domains in proteins of unknown spatial structure, as the construction of the ADM for a given protein requires knowledge of only its amino acid sequence.
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Relation between sequence similarity and structural similarity in proteins. Role of important properties of amino acids
TL;DR: The most important properties that determine the three-dimensional structure of a protein are conserved properties, i.e., are those that have been conserved during evolution, and bulk and hydrophobicity are more important than other properties, such as the preference for adopting a specific backbone structure.
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Nature of the Unfolded State of Ribonuclease A: Effect of Cis−Trans X−Pro Peptide Bond Isomerization†
TL;DR: The results of these experiments support the conclusion that the different unfolded species arise from cis-trans isomerizations at the X-Pro peptide bonds of Pro 93, 114, and 117 in the unfolded state of the protein.
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Stability of Like and Oppositely Charged Organic Ion Pairs in Aqueous Solution
TL;DR: In this paper, polarizable continuum model (PCM) ab initio molecular orbital calculations were carried out to investigate the stability of ionic pairs in aqueous solution, and three organic ions, methylacetate, methylammonium and guanidinium, were treated.
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