Harold A. Scheraga
Cornell University
1160 Papers
25.6K Citations
Harold A. Scheraga is an academic researcher from Cornell University. The author has contributed to research in topics: Protein structure & Protein folding. The author has an hindex of 120, co-authored 1152 publications. Previous affiliations of Harold A. Scheraga include University of Gdańsk & National University of San Luis.
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Papers
Monte Carlo-minimization approach to the multiple-minima problem in protein folding.
Zhenqin Li,Harold A. Scheraga +1 more
TL;DR: The Monte Carlo-minimization method has located the lowest-energy minimum thus far reported for the brain pentapeptide [Met5]enkephalin in the absence of water, presumably it is the global minimum-energy structure.
1.4K
Global optimization of clusters, crystals, and biomolecules
TL;DR: Some recent progress in finding the global minima of potential energy functions is described, focusing on applications of the simple "basin-hopping" approach to atomic and molecular clusters and more complicated hypersurface deformation techniques for crystals and biomolecules.
Experimental and theoretical aspects of protein folding.
Anfinsen Cb,Harold A. Scheraga +1 more
TL;DR: The development of conformational energy calculation procedures will enable the three-dimensional structure of a native protein to be predicted from the knowledge of its amino acid sequence and its interactions with the solvent in which it is dissolved.
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