Hari K. Narayan
University of California, San Diego
34 Papers
32 Citations
Hari K. Narayan is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 7, co-authored 21 publications. Previous affiliations of Hari K. Narayan include Morgan Stanley Children's Hospital & University of Pennsylvania.
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Papers
Detailed Echocardiographic Phenotyping in Breast Cancer Patients: Associations With Ejection Fraction Decline, Recovery, and Heart Failure Symptoms Over 3 Years of Follow-Up.
Hari K. Narayan,Brian S. Finkelman,Benjamin French,Theodore Plappert,David Hyman,Amanda M. Smith,Kenneth B. Margulies,Bonnie Ky +7 more
TL;DR: In this article, the longitudinal effects of commonly used therapies, including doxorubicin and trastuzumab, on cardiac remodegmentation in patients with breast cancer were investigated.
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Noninvasive Measures of Ventricular-Arterial Coupling and Circumferential Strain Predict Cancer Therapeutics-Related Cardiac Dysfunction
Hari K. Narayan,Benjamin French,Abigail Khan,Theodore Plappert,David Hyman,Akinyemi Bajulaiye,Susan M. Domchek,Angela DeMichele,Amy S. Clark,Jennifer M. Matro,Angela R. Bradbury,Kevin Fox,Joseph R. Carver,Bonnie Ky +13 more
TL;DR: Over an extended follow-up time, ventricular-arterial coupling and circumferential strain were strongly predictive of CTRCD, suggesting a noninvasive strategy to identify high-risk patients prior to, during, and after cardiotoxic cancer therapy.
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Comprehensive Assessment of Changes in Left Ventricular Diastolic Function With Contemporary Breast Cancer Therapy
Jenica N. Upshaw,Brian S. Finkelman,Rebecca A. Hubbard,Amanda M. Smith,Hari K. Narayan,Linzi Arndt,Susan M. Domchek,Angela DeMichele,Kevin Fox,Payal D. Shah,Amy S. Clark,Angela R. Bradbury,Jennifer M. Matro,Srinath Adusumalli,Joseph R. Carver,Bonnie Ky +15 more
TL;DR: A modest, persistent worsening of diastolic function is observed with contemporary breast cancer therapy, with reductions in the E/A ratio, lateral and septal e' velocities, and increases in E/e' (p < 0.01).
113
Arginine-Nitric Oxide Metabolites and Cardiac Dysfunction in Patients With Breast Cancer.
Brian S. Finkelman,Mary E. Putt,Teresa Wang,Le Wang,Hari K. Narayan,Susan M. Domchek,Angela DeMichele,Kevin Fox,Jennifer M. Matro,Payal D. Shah,Amy S. Clark,Angela R. Bradbury,Vivek Narayan,Joseph R. Carver,W.H. Wilson Tang,Bonnie Ky +15 more
TL;DR: In breast cancer patients undergoing doxorubicin therapy, early alterations in arginine-NO metabolite levels occurred, and early biomarker changes were associated with a greater CTRCD rate, highlighting the potential mechanistic and translational relevance of this pathway to CTRCD.
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Abnormalities in 3-Dimensional Left Ventricular Mechanics With Anthracycline Chemotherapy Are Associated With Systolic and Diastolic Dysfunction.
Kathleen W. Zhang,Brian S. Finkelman,Gaurav Gulati,Hari K. Narayan,Jenica N. Upshaw,Vivek Narayan,Ted Plappert,Virginia Englefield,Amanda M. Smith,Carina Zhang,W. Gregory Hundley,Bonnie Ky,Bonnie Ky +12 more
TL;DR: The 3D LVEF and strain measures are associated with concurrent and subsequent systolic dysfunction, and concurrent diastolic dysfunction after anthracyclines, and future research is needed to define the mechanisms and clinical relevance of abnormal 3D mechanics.
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