Harald Paganetti
Harvard University
400 Papers
1.7K Citations
Harald Paganetti is an academic researcher from Harvard University. The author has contributed to research in topics: Proton therapy & Medicine. The author has an hindex of 67, co-authored 367 publications. Previous affiliations of Harald Paganetti include Paul Scherrer Institute & AT&T.
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Papers
Radiobiological Intercomparison of the 160 MeV and 230 MeV Proton Therapy Beams at the Harvard Cyclotron Laboratory and at Massachusetts General Hospital
Bradly G. Wouters,L. D. Skarsgard,Leo E. Gerweck,A Carabe-Fernandez,Michelle Wong,Ralph E. Durand,Deanna Nielson,Marc R. Bussière,Miles Wagner,Peter J. Biggs,Harald Paganetti,Herman D. Suit +11 more
TL;DR: The purpose of this study was to determine the relative biological effectiveness (RBE) along the axis of two range-modulated proton beams (160 and 230 MeV) and the depth and the dose dependence of RBE were investigated.
Monte Carlo simulations will change the way we treat patients with proton beams today
TL;DR: How simulations have the potential to change clinical practice particularly in proton therapy is outlined, which will impact treatment outcome analysis, reduce treatment volumes and help understand proton-induced radiation biology.
Range verification of passively scattered proton beams based on prompt gamma time patterns
TL;DR: This paper validated the hadronic models used in TOPAS by comparing simulations and prompt gamma spectrometry measurements published in the literature and performed four-dimensional Monte Carlo simulations using TOPAS to show the validity and accuracy of the technique.
Direct absorbed dose to water determination based on water calorimetry in scanning proton beam delivery
Arman Sarfehnia,Benjamin Clasie,E Chung,Hsiao-Ming Lu,J Flanz,E Cascio,Martijn Engelsman,Harald Paganetti,Jan Seuntjens +8 more
TL;DR: It is demonstrated that a primary absorbed dose standard based on water calorimetry is feasible in scattered and scanned proton beams and agrees with the results from TRS-398 well to within 1-sigma uncertainty.
Recent developments and comprehensive evaluations of a GPU-based Monte Carlo package for proton therapy.
Nan Qin,Pablo Botas,Pablo Botas,Drosoula Giantsoudi,Jan Schuemann,Zhen Tian,Steve B. Jiang,Harald Paganetti,Xun Jia +8 more
TL;DR: Recent updates on gPMC in terms of its accuracy, portability, and functionality, as well as comprehensive tests on this graphics-processing unit (GPU)-based MC tool are reported.