Haojing Chang
Peking University
7 Papers
25 Citations
Haojing Chang is an academic researcher from Peking University. The author has contributed to research in topics: Protocell & Chemistry. The author has an hindex of 5, co-authored 7 publications.
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Papers
Fission and Internal Fusion of Protocell with Membraneless "Organelles" Formed by Liquid-Liquid Phase Separation.
TL;DR: This study highlights that liquid-liquid phase separation of biopolymers is a powerful strategy to construct hierarchically structured protocells resembling the morphology and functions of living cells, and provides a step towards a better understanding of the transition mechanism from non-living to living matter under prebiotic conditions.
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Electric field-induced circulation and vacuolization regulate enzyme reactions in coacervate-based protocells.
TL;DR: This work demonstrates that circulation and vacuolization can occur simultaneously inside the droplet in the presence of an electric field and provides a new strategy to create non-equilibrium dynamic behaviors in molecularly crowded membrane-free synthetic protocells.
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Mass Transport in Coacervate-Based Protocell Coated with Fatty Acid under Nonequilibrium Conditions
TL;DR: This work prepares a hybrid protocell model by coating sodium oleate on the coacervate droplet constituted by poly(l-lysine) and oligonucleotide and investigates the transport of different molecules under electric field to make a step toward the nonequilibrium functionalization of synthetic protocells capable of biomimetic operations.
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Core-Corona Structure Formed by Hyaluronic Acid and Poly(L-lysine) via Kinetic Path
TL;DR: In this paper, the structure and kinetics of the complex formed by hyaluronic acid (HA) and poly(L-lysine) (PLL) were studied by time-resolved laser light scattering, TEM, and AFM.
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Protocells with hierarchical structures as regulated by liquid-liquid and liquid-solid phase separations.
TL;DR: In this article, the authors built composite droplets with PLL/oligo/oligocomp solid particles randomly distributed inside a PLL liquid coacervate, where circulation and vacuolization under an electric field drive the particles into a fibrous structure and even clusters.
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