Hao Yan
University of Minnesota
12 Papers
3 Citations
Hao Yan is an academic researcher from University of Minnesota. The author has contributed to research in topics: Folliculogenesis & Oocyte. The author has an hindex of 8, co-authored 10 publications. Previous affiliations of Hao Yan include China Agricultural University & Ningxia University.
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Papers
Characterization of Polysaccharides with Antioxidant and Hepatoprotective Activities from the Wild Edible Mushroom Russula vinosa Lindblad
TL;DR: It is suggested that RVLWP and RVLAP protect the liver from CCl4-induced hepatic damage via antioxidant mechanisms.
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CDC42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes.
Hao Yan,Jiawei Zhang,Jia Wen,Yibo Wang,Wanbao Niu,Zhen Teng,Tongtong Zhao,Yanli Dai,Yan Zhang,Chao Wang,Yingying Qin,Guoliang Xia,Hua Zhang +12 more
TL;DR: The results reveal that CDC42 controls the activation of primordial follicles in the mammalian ovary and that increasing the activity of CDC42 with specific activators might improve the efficiency of in vitro activation approaches, opening avenues for infertility treatments.
SIRT1 facilitates primordial follicle recruitment independent of deacetylase activity through directly modulating Akt1 and mTOR transcription
Tuo Zhang,Xinhua Du,Lihua Zhao,Meina He,Lin Lin,Chuanhui Guo,Xinran Zhang,Jun Han,Hao Yan,Kun Huang,Guanghong Sun,Lei Yan,Bo Zhou,Guoliang Xia,Guoliang Xia,Ying Ying Qin,Chao Wang +16 more
TL;DR: SIRT1 facilitates primordial follicle recruitment independent of deacetylase activity through directly modulating Akt1 and mTOR transcription, and could be a candidate strategy to develop more efficient procedures for future clinical treatment of infertility.
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Oocyte-derived E-cadherin acts as a multiple functional factor maintaining the primordial follicle pool in mice.
Hao Yan,Jia Wen,Tuo Zhang,Wenying Zheng,Meina He,Kun Huang,Qirui Guo,Qian Chen,Yi Yang,Guangcun Deng,Jinrui Xu,Zhiqing Wei,Hua Zhang,Guoliang Xia,Guoliang Xia,Chao Wang +15 more
TL;DR: It is demonstrated that E-cadherin in oocytes of PFs plays an indispensable role in the maintenance of the PF pool by facilitating follicular structural stability and regulating NOBOX expression.
JAK signaling regulates germline cyst breakdown and primordial follicle formation in mice.
Kun Huang,Ye Wang,Tuo Zhang,Meina He,Guanghong Sun,Jia Wen,Hao Yan,Han Cai,Changfu Yong,Guoliang Xia,Chao Wang +10 more
TL;DR: It is shown that oocyte-derived Janus kinase (JAK) signaling is vital for germline cyst breakdown and primordial follicle formation in vitro and that JAK signaling regulates oocyte loss and pregranulosa cell proliferation in the fetal mouse ovary.