Hao Liu
Zhejiang University
14 Papers
42 Citations
Hao Liu is an academic researcher from Zhejiang University. The author has contributed to research in topics: Liver transplantation & Cell growth. The author has an hindex of 11, co-authored 14 publications.
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Papers
Tumor-derived exosomes promote tumor self-seeding in hepatocellular carcinoma by transferring miRNA-25-5p to enhance cell motility.
Hao Liu,Wei Chen,Xiao Zhi,Enjiang Chen,Tao Wei,Jian Zhang,Jian Shen,Liqiang Hu,Bin Zhao,Xin-Hua Feng,Xueli Bai,Tingbo Liang +11 more
TL;DR: It is confirmed that circulating tumor cell uptake of tumor-derived exosomes, which are increasingly recognized as key instigators of cancer progression by facilitating cell–cell communication, promoted tumor self-seeding by enhancing the invasive and migration capability of recipient HCC cells.
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G protein-coupled estrogen receptor deficiency accelerates liver tumorigenesis by enhancing inflammation and fibrosis.
Tao Wei,Wei Chen,Liang Wen,Jian Zhang,Qi Zhang,Jiaqi Yang,Hao Liu,Bryan Wei Chen,Yue Zhou,Xin-Hua Feng,Qi Yang,Xueli Bai,Tingbo Liang +12 more
TL;DR: GPER protects against HCC tumorigenesis through regulating inflammatory responses rather than directly acting on tumor cells, therefore, GPER activation may be a potential strategy for prevention and treatment of HCC.
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Inhibition of mTORC2 induces cell cycle arrest and enhances the cytotoxicity of doxorubicin by suppressing MDR1 expression in HCC cells
Bryan Wei Chen,Wei Chen,Hui Liang,Hao Liu,Chao Liang,Xiao Zhi,Li Qiang Hu,Xia Zhen Yu,Tao Wei,Tao Ma,Fei Xue,Lei Zheng,Bin Zhao,Xin-Hua Feng,X. Bai,T. Liang +15 more
TL;DR: The findings provide a rationale for dual mTORC1/mTORC2 inhibitors, such as OSI-027, as monotherapy or in combination with cytotoxic agents to treat HCC, and synergized with doxorubicin for the antiproliferative efficacy.
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Mesenchymal stem cells administered after liver transplantation prevent acute graft-versus-host disease in rats.
Xue-Feng Xia,Wei Chen,Tao Ma,Guodong Xu,Hao Liu,Chao Liang,Xueli Bai,Yun Zhang,Yong He,Tingbo Liang +9 more
TL;DR: Post‐LT administration of MSCs of either donor or recipient origin could prevent the onset of LT‐aGVHD in the rat model, and they could increase the Treg ratio in a mixed lymphocyte reaction (MLR) and lead to a greater reduction in MLR proliferation in vitro.
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NSC 74859 enhances doxorubicin cytotoxicity via inhibition of epithelial–mesenchymal transition in hepatocellular carcinoma cells
Qida Hu,Wei Chen,Tian-Lian Yan,Tao Ma,Cong-Lin Chen,Chao Liang,Qi Zhang,Xue-Feng Xia,Hao Liu,Xiao Zhi,Xiaoxiao Zheng,Xueli Bai,Xiazhen Yu,Tingbo Liang +13 more
TL;DR: Data indicate NSC 74859 co-administration enhances doxorubicin cytotoxicity by inhibiting STAT3 in epithelial HCC cells, and STAT3 deactivation and associated EMT attenuation contribute to the synergistic anti-tumor effects of combined NSC74859/doxorubsicin therapy.
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