Hao Chen
Wuhan University
21 Papers
16 Citations
Hao Chen is an academic researcher from Wuhan University. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 13, co-authored 21 publications.
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Papers
Tumor-Derived Exosomal Long Noncoding RNAs as Promising Diagnostic Biomarkers for Prostate Cancer.
Yuhui Wang,Jia Ji,Bi-Cheng Wang,Hao Chen,Zhong-Hua Yang,Kun Wang,Chang-Liang Luo,Wu-Wen Zhang,Fu-Bing Wang,Xiao-Lian Zhang +9 more
TL;DR: The isolation of tumor-derived exosomes by dual-antibody-functionalized immunoaffinity systems and detection of their lncRNAs in plasma may lead to the identification of suitable biomarkers, with potential diagnostic utility.
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Differential expression of plasma microRNA-125b in hepatitis B virus-related liver diseases and diagnostic potential for hepatitis B virus-induced hepatocellular carcinoma
TL;DR: The expression profile of this miRNA in the plasma of healthy subjects and patients with chronic HBV‐related liver diseases is investigated to confirm the feasibility of this circulating miRNA as a differential diagnostic biomarker for HBV-induced HCC (HBV‐HCC).
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Liquid Biopsy of Hepatocellular Carcinoma: Circulating Tumor-Derived Biomarkers
TL;DR: This review focuses on the recent developments in the field of “liquid biopsy” as well as the diagnostic and prognostic significance of CTCs and cfNAs in HCC patients.
Capture and Release of Cancer Cells by Combining On-Chip Purification and Off-Chip Enzymatic Treatment.
Xiaolei Yu,Bingrui Wang,Nangang Zhang,Chang-Qing Yin,Hao Chen,Lingling Zhang,Bo Cai,Zhaobo He,Lang Rao,Wei Liu,Fu-Bing Wang,Shishang Guo,Xing-Zhong Zhao +12 more
TL;DR: By combining on-chip purification and off-chip enzymatic treatment, this work demonstrates a two-stage strategy to enhance the purity of captured cancer cells from blood samples.
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Identification of an aptamer through whole cell-SELEX for targeting high metastatic liver cancers
Yuan Rong,Hao Chen,Xuefeng Zhou,Chang-Qing Yin,Bi-Cheng Wang,Chun-Wei Peng,Shao-Ping Liu,Fu-Bing Wang +7 more
TL;DR: Treatment of highly metastatic cells with LY-1 led to reduced migration and invasiveness of HCCLM9 cells in vitro and suppression of xenograft growth in vivo, and demonstrated the tumor targeting and tumor suppressive effects of Ly-1, which could be a promising molecular probe for metastatic HCC and a potential candidate of chemotherapy for metastatics HCC.