Hao Chai
Nanjing Medical University
14 Papers
3 Citations
Hao Chai is an academic researcher from Nanjing Medical University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 4, co-authored 4 publications.
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Papers
Pyruvate kinase M2 affects liver cancer cell behavior through up-regulation of HIF-1α and Bcl-xL in culture
Tianfu Dong,Youde Yan,Hao Chai,Sheng-lin Chen,Xinkui Xiong,Daoyi Sun,Yue Yu,Lei Deng,Feng Cheng +8 more
TL;DR: The current findings demonstrate that PKM2 is an active protein kinase, and promotes liver cancer cell proliferation by up-regulating HIF-1α and Bcl-xL expression.
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Transplantation of ATP7B-transduced bone marrow mesenchymal stem cells decreases copper overload in rats.
Shenglin Chen,Cun-hua Shao,Tianfu Dong,Hao Chai,Xinkui Xiong,Daoyi Sun,Long Zhang,Yue Yu,Ping Wang,Feng Cheng +9 more
TL;DR: It is demonstrated that transplantation of MSCsATP7B into IRP-plus-RT preconditioned LEC rats decreased copper overload and was associated with an increase in MSC engraftment and repopulation.
SOST gene suppression stimulates osteocyte Wnt/β-catenin signaling to prevent bone resorption and attenuates particle-induced osteolysis
TL;DR: The most common cause for prosthetic revision surgery is wear particle-induced periprosthetic osteolysis, which leads to aseptic loosening of the prosthesis as discussed by the authors .
MiR-937-3p promotes metastasis and angiogenesis and is activated by MYC in lung adenocarcinoma
Zijian Ma,Ganyi Chen,Yiqi Chen,Zizhang Guo,Hao Chai,Yuling Tang,Lin Zheng,Ke Wei,Chunfeng Pan,Zhifei Ma,Yang Xia,Aiping Zhang +11 more
TL;DR: Wang et al. as mentioned in this paper used miRNA microarray to analyze the expression of miRNA in lung adenocarcinoma (LUAD) tissue and found that miR-937-3p high-expression has an effect on cell invasion and metastasis.
Overexpressed DDX3x promotes abdominal aortic aneurysm formation and activates AKT in ApoE knockout mice.
Yifei Zhou,Hao Chai,Yun-xin Hu,Renjie Liu,Hongwei Jiang,Ruihua Fan,Wen Chen,Fuhua Huang,Xin Chen +8 more
TL;DR: In this paper , the authors used an adeno-associated virus to construct gene-overexpressing mice to induce abdominal aortic aneurysm development through AngII infusion.
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