Hans M. Warrick
Stanford University
27 Papers
356 Citations
Hans M. Warrick is an academic researcher from Stanford University. The author has contributed to research in topics: Myosin & Myosin head. The author has an hindex of 18, co-authored 27 publications.
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Papers
Quantized velocities at low myosin densities in an in vitro motility
TL;DR: An in vitro motility assay has been developed in which single actin filaments move on one or a few heavy meromyosin (HMM) molecules, which is consistent with the conventional swinging crossbridge model for myosin function.
190
Conserved protein domains in a myosin heavy chain gene from Dictyostelium discoideum.
TL;DR: The 2116-amino acid myosin heavy chain sequence from Dictyostelium discoideum was determined from DNA sequence analysis of the cloned gene, finding that certain features that are present in the head region of nematode and mammalian muscle myosins, and that have been assumed to be important for myOSin function, are missing in the DictYostelio myosIn sequence.
159
Functional diversity among a family of human skeletal muscle myosin motors.
TL;DR: A mammalian muscle cell expression system and the functional analysis of all six recombinant human type II skeletal muscle myosin isoforms indicate that they likely have distinct functions in muscle and show that ATPase activity and motility are generally correlated for human skeletal musclemyosins.
127
Quantitation of the distribution and flux of myosin-II during cytokinesis
TL;DR: Quantitation of the distribution and flux of a mutant myosin-II that is defective in phosphorylation-dependent thick filament disassembly confirms that heavy chainosphorylation regulates normal recruitment to the furrow cortex.
A structural model for phosphorylation control of Dictyostelium myosin II thick filament assembly.
TL;DR: Evidence is provided that thick filament assembly control involves the folding of myosin II into a bent monomer, which is unable to incorporate into thick filaments.