Hanping Feng
University of Maryland, Baltimore
80 Papers
465 Citations
Hanping Feng is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Clostridium difficile & Clostridium difficile toxin B. The author has an hindex of 28, co-authored 75 publications. Previous affiliations of Hanping Feng include Harvard University & Tufts University.
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Papers
Stressed apoptotic tumor cells express heat shock proteins and elicit tumor-specific immunity.
TL;DR: The findings indicate that tumor immunogenicity is dependent on whether cells are stressed before apoptosis induction and suggest that the immune system is capable of distinguishing between stressed and nonstressed cells undergoing programmed cell death.
164
Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium
Guilin Yang,Boping Zhou,Jufang Wang,Xiangyun He,Xingmin Sun,Weijia Nie,Saul Tzipori,Hanping Feng +7 more
TL;DR: The full length and active recombinant TcdA and TcdB in Bacillus megaterium are generated and their biological activities were found to be similar to their native counterparts after an extensive examination.
Mouse relapse model of Clostridium difficile infection.
Xingmin Sun,Haiying Wang,Haiying Wang,Yongrong Zhang,Yongrong Zhang,Kevin Chen,Barbara J. Davis,Hanping Feng +7 more
TL;DR: A conventional mouse model of recurrence/relapse CDI is established that allows for future investigations of the role of the host immune response in the disease's pathogenesis and permits critical testing of new therapeutics targeting recurrent disease.
128
Exogenous stress proteins enhance the immunogenicity of apoptotic tumor cells and stimulate antitumor immunity.
TL;DR: Evidence is provided that when purified heat shock protein 70 or chaperone-rich cell lysate (CRCL) from syngeneic normal tissue is used as an adjuvant with nonimmunogenic apoptotic tumor cells in vaccination, potent antitumor immunity can be generated.
119
The Enterotoxicity of Clostridium Difficile Toxins
TL;DR: This review considers the mechanisms of TcdA- and TcdB-induced enterotoxicity, and recent developments in this field.
114