Hannes Lohi
University of Helsinki
254 Papers
867 Citations
Hannes Lohi is an academic researcher from University of Helsinki. The author has contributed to research in topics: Biology & Population. The author has an hindex of 47, co-authored 228 publications. Previous affiliations of Hannes Lohi include Technische Universität München & Hacettepe University.
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Papers
Whole Genome Sequencing Reveals Multiple Linked Genetic Variants on Canine Chromosome 12 Associated with Risk for Symmetrical Lupoid Onychodystrophy (SLO) in the Bearded Collie.
TL;DR: In this article, a case-control association was employed on whole genome sequencing data to uncover putative causative variants in lupoid onychodystrophy within the CFA12 and CFA17 associated regions.
Simultaneous allergic traits in dogs and their owners are associated with living environment, lifestyle and microbial exposures
Jenni Lehtimäki,Hanna Sinkko,Anna Hielm-Björkman,Tiina Laatikainen,Lasse Ruokolainen,Hannes Lohi +5 more
TL;DR: It is concluded that dogs and humans can be predisposed to allergy in response to same risk factors, and other factors than environmental microbial exposures can mediate the effect or furry dog and furless human skin select different taxa.
TSEN54 missense variant in Standard Schnauzers with leukodystrophy.
Theresa Störk,Jasmin Nessler,Linda Anderegg,Enrice Hünerfauth,Isabelle Schmutz,Vidhya Jagannathan,Kaisa Kyöstilä,Hannes Lohi,Wolfgang Baumgärtner,Andrea Tipold,Tosso Leeb +10 more
TL;DR: The results suggest that TSEN54:c.371G>A causes the leukodystrophy, and the identification of a candidate causative variant enables genetic testing so that the unintentional breeding of affected Standard Schnauzers can be avoided in the future.
Genome-Wide Association Study in Dachshund: Identification of a Major Locus Affecting Intervertebral Disc Calcification
Mette Mogensen,Peter Karlskov-Mortensen,Helle Friis Proschowsky,Frode Lingaas,Anu K. Lappalainen,Hannes Lohi,Vibeke Jensen,Merete Fredholm +7 more
TL;DR: It is suggested that a major locus on chromosome 12 harbors genetic variations affecting the development of intervertebral disc calcification in Dachshund.
Maternal Inheritance of a Recessive RBP4 Defect in Canine Congenital Eye Disease
Maria Kaukonen,Sean Woods,Saija Ahonen,Seppo Lemberg,Maarit Hellman,Marjo K. Hytönen,Perttu Permi,Thomas M Glaser,Hannes Lohi +8 more
TL;DR: The results demonstrate a mode of recessive maternal inheritance, with a physiological basis, and they extend previous observations on dominant-negative RBP4 alleles in humans, which are known to be a risk factor for ocular birth defects.