Hannah Meyer

TL;DR: In this article, a high-fat diet (HFD) reduces the expression of the major histocompatibility complex class II (MHC class II) genes in intestinal epithelial cells, including ISCs.

TL;DR: PhenotypeSimulator is developed, a comprehensive phenotype simulation scheme that can model multiple traits with multiple underlying genetic loci as well as complex covariate and observational noise structure.

TL;DR: This work developed LiMMBo, a new approach for the joint analysis of high-dimensional phenotypes that builds on linear mixed models with bootstrapping, thereby providing robust control for population structure and other confounding factors, and the model scales to larger datasets with up to hundreds of phenotypes.

TL;DR: An eGFR model for patients with cancer compatible with both creatinine measurement methods and outperforms previous models is presented and should be examined prospectively as a practice-changing standard of care for eG FR-based carboplatin dosing.