Hangyu Li
China Medical University (PRC)
40 Papers
92 Citations
Hangyu Li is an academic researcher from China Medical University (PRC). The author has contributed to research in topics: Autophagy & Biology. The author has an hindex of 20, co-authored 38 publications.
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Papers
The emerging role of exosome-derived non-coding RNAs in cancer biology.
Qing Fan,Liang Yang,Xiaodong Zhang,Xueqiang Peng,Shibo Wei,Dongming Su,Zhenhua Zhai,Xiangdong Hua,Hangyu Li +8 more
TL;DR: The promotion of tumor development by exosomal ncRNAs including chemotherapy resistance, metastasis and the prospective use of exosomes in cancer diagnosis and treatment are reviewed.
195
Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress
Xiaodong Zhang,Yan Li,Yingbo Ma,Liang Yang,Tao Wang,Xin Meng,Zhi-Hong Zong,Xun Sun,Xiangdong Hua,Hangyu Li +9 more
TL;DR: A new regulatory mechanism of hypoxia-mediated HCC metabolism is described, and YAP might be a promising therapeutic target in HCC.
Autophagy promotes metastasis and glycolysis by upregulating MCT1 expression and Wnt/β-catenin signaling pathway activation in hepatocellular carcinoma cells
Qing Fan,Liang Yang,Xiaodong Zhang,Yingbo Ma,Yan Li,Lei Dong,Zhi-Hong Zong,Xiangdong Hua,Dongming Su,Hangyu Li,Jingang Liu +10 more
TL;DR: The connection between autophagy and glucose metabolism in HCC cells is described and may provide a potential therapeutic target for HCC treatment.
Autophagy: A novel mechanism of chemoresistance in cancers.
Xinyu Li,Yong Zhou,Yongshuang Li,Liang Yang,Yingbo Ma,Xueqiang Peng,Shuo Yang,Jingang Liu,Hangyu Li +8 more
TL;DR: The role of autophagy is identified and recent advances in the identification of the mechanism by which it is implicated in drug resistance are described, with a focus on the mode of action, and validation as potential therapeutics are described.
180
The role of YAP/TAZ activity in cancer metabolic reprogramming
TL;DR: Progress is examined in research into the regulatory mechanisms of YAP/TAZ on glucose metabolism, fatty acid metabolism, mevalonate metabolism, and glutamine metabolism in cancer cells to provide new strategies and targets for the selective therapy of metabolism-related cancers.