Hanan S. El-Abhar
Cairo University
84 Papers
163 Citations
Hanan S. El-Abhar is an academic researcher from Cairo University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 22, co-authored 60 publications. Previous affiliations of Hanan S. El-Abhar include University of Marburg & Future University in Egypt.
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Papers
Prunetin in a GPR30-dependent manner mitigates renal ischemia/reperfusion injury in rats via interrupting indoxyl sulfate/TLR4/TRIF, RIPK1/RIPK3/MLKL, and RIPK3/PGAM5/DRP-1 crosstalk
Ahmed B. Hamed,Hanan S. El-Abhar,Dalaal M. Abdallah,Kawkab A. Ahmed,Yasmin S. Abulfadl +4 more
TL;DR: Punetin exhibited a significant reno-therapeutic effect evidenced by the enhancement of renal morphology and function, the suppression of the inflammatory cascade indoxyl sulfate/TLR4/TRIF, which turns off the activated/phosphorylated necroptotic trajectory RIPK1/RIPK3/MLKL, while enhancing caspase-8.
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The Enzalutamide and EPI-001 modulate cell proliferation and metastasis markers in T47D by targeting AR/ARV7
Belal M Ali,Hanan S. El-Abhar,Dalaal M. Abdallah,Ghada Mohamed,Marwa M. Sharaky,Samia A. Shouman,Marwa Kamel +6 more
TL;DR: This in-vitro study highlights the importance of targeting AR/ARv7 using Enzalutamide and EPI-001 in decreasing proliferation cell markers, EMT, and metastasis in ER+ BC cells, findings that may have great impact in the treatment of ER+BC.
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Anandamide modulates WNT-5A/BCL-2, IP3/NFATc1, and HMGB1/NF-κB trajectories to protect against mercuric chloride-induced acute kidney injury
Dalaal M. Abdallah,Mahmoud M Kamal,N. Aly,Hanan S. El-Abhar +3 more
TL;DR: The results verify the reno-protective potential of AEA against HgCl_2-induced kidney injury by its anti-inflammatory, antioxidant, and anti-apoptotic capacities by modulating WNT-5A/BCL-2, IP3/NFATC1, HMGB-1/RAGE/NF-κB, caspase-1/IL-18, and caspase-3/BCL-2 cues.
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Outcome and Safety of Colistin Usage in Pediatric Cancer Patients with Carbapenem-Resistant Enterobacteriaceae Bacteremia at Children Cancer Hospital Egypt
TL;DR: In this paper , an observational, prospective cohort study from May 2017 to October 2017 in Children's Cancer Hospital Egypt 57,357 patients who had blood stream infections due to CRE receiving intravenous colistin were prospectively enrolled.
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