Han Wang
Yunnan Normal University
15 Papers
3 Citations
Han Wang is an academic researcher from Yunnan Normal University. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 4, co-authored 9 publications.
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Papers
Mosaic loss of human Y chromosome: what, how and why
TL;DR: The micronucleation hypothesis and centromere-dysfunction and telomere-attrition models are proposed to explain how mosaic LOY occurs and why ChrY is prone to lose and it is believed an improved understanding of mosaic LOy will open new pathways to modify and increase healthy aging in males.
88
Differences in the Effects of EGCG on Chromosomal Stability and Cell Growth between Normal and Colon Cancer Cells.
TL;DR: EGCG could significantly induce chromosome instability in COLO205 cells and trigger apoptosis and inhibition of cell division, suggesting that EGCG exhibits different genetic and cytological effects in normal and colon cancer cells.
34
Shelterin differentially respond to oxidative stress induced by TiO2-NPs and regulate telomere length in human hepatocytes and hepatocarcinoma cells in vitro
TL;DR: The differentially responses of the tested components of shelterin and Nrf-2 to oxidative stress induced by TiO2-NPs led to the weakened telomere protection in normal cells and effective telomeres maintenance in cancer cells, respectively.
18
High homocysteine promotes telomere dysfunction and chromosomal instability in human neuroblastoma SH-SY5Y cells.
TL;DR: There is cross-talk between Hcy and TL in tumor cells and supports the concept that high Hcy inhibits cell division and promotes the death of tumor cells by abnormal elongation of TL and elevation of CIN.
6
MicroRNA-22-3p and MicroRNA-149-5p Inhibit Human Hepatocellular Carcinoma Cell Growth and Metastasis Properties by Regulating Methylenetetrahydrofolate Reductase
TL;DR: The results of the study suggest that miRNA-22-3p and mi RNA-149-5p inhibit tumor growth and metastasis properties may be by regulating MTHFR and that they exert anticancer effects in hepatocellular carcinoma cells.