Haley Strouf
Massachusetts Institute of Technology
4 Papers
1 Citations
Haley Strouf is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Medicine & Intravasation. The author has an hindex of 1, co-authored 2 publications.
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Papers
Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice.
Bashar Hamza,Alex B. Miller,Lara Meier,Lara Meier,Max A. Stockslager,Sheng Rong Ng,Emily M. King,Lin Lin,Kelsey L. DeGouveia,Kelsey L. DeGouveia,Nolawit Mulugeta,Nicholas L. Calistri,Haley Strouf,Christina Bray,Felicia Rodriguez,William A. Freed-Pastor,William A. Freed-Pastor,Christopher R. Chin,Grissel C. Jaramillo,Megan L. Burger,Robert A. Weinberg,Alex K. Shalek,Tyler Jacks,Scott R. Manalis +23 more
TL;DR: In this paper, the authors demonstrate an approach for measuring endogenous CTC kinetics by continuously exchanging CTC-containing blood over several hours between unanesthetized, tumor-bearing mice and healthy, tumor free counterparts.
Removal of a partial genomic duplication restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer
Fernando J. Bustos,Swarna Pandian,Henny Haensgen,Jian-Ping Zhao,Haley Strouf,Matthias Heidenreich,Lukasz Swiech,Benjamin E. Deverman,Viviana Gradinaru,Feng Zhang,Martha Constantine-Paton +10 more
TL;DR: It is found that editing the flailer gene in primary cortical neurons reverts synaptic transport and transmission defects and long-term depression, disrupted in Flailer animals, is recovered after gene editing.
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Removal of a genomic duplication by double-nicking CRISPR restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer
Fernando J. Bustos,Swarna Pandian,Jian-Ping Zhao,Haley Strouf,Matthias Heidenreich,Lukasz Swiech,Benjamin E. Deverman,Viviana Gradinaru,Feng Zhang,Martha Constantine-Paton +9 more
TL;DR: In this article , the authors demonstrate the use of DN-CRISPRs to remove a 700bp genomic duplication in vitro and in vivo, but they have not been used to remove more gene regions <100bp successfully and with high efficiency.
Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice
Bashar Hamza,Alex B. Miller,Lara Meier,Lara Meier,Max A. Stockslager,Emily M. King,Sheng Rong Ng,Kelsey L. DeGouveia,Kelsey L. DeGouveia,Nolawit Mulugeta,Nicholas L. Calistri,Haley Strouf,Lin Lin,Christopher R. Chin,Robert A. Weinberg,Alex K. Shalek,Tyler Jacks,Scott R. Manalis +17 more
TL;DR: This work demonstrates an approach for measuring endogenous CTC kinetics by continuously exchanging CTC-containing blood over several hours between un-anesthetized, tumor-bearing mice and healthy, tumors-free counterparts and envision that this technique will help further elucidate the role of CTCs and the rate-limiting steps in metastasis.