Haiyan Fu
Southern Medical University
11 Papers
Haiyan Fu is an academic researcher from Southern Medical University. The author has contributed to research in topics: Kidney & Medicine. The author has an hindex of 9, co-authored 11 publications.
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Papers
Tubule-Derived Wnts Are Required for Fibroblast Activation and Kidney Fibrosis
Dong Zhou,Haiyan Fu,Lu Zhang,Ke Zhang,Yali Min,Liangxiang Xiao,Lin Lin,Sheldon I. Bastacky,Youhua Liu +8 more
TL;DR: Tunule-derived Wnts have an essential role in promoting fibroblast activation and kidney fibrosis via epithelial-mesenchymal communication and biopsy specimens from patients with CKD show increased expression of multiple Wnt proteins.
Limonin ameliorates ulcerative colitis by regulating STAT3/miR-214 signaling pathway
Shijia Liu,Shufang Zhang,Xiangyu Lv,Jiawei Lu,Cong Ren,Zhiqin Zeng,Lufeng Zheng,Xianke Zhou,Haiyan Fu,Dong Zhou,Yugen Chen +10 more
TL;DR: Limonin markedly reduced DAI, intestinal damages, and the levels of pro-inflammatory cytokines, such as TNF-α and IL-6 in UC in vivo and in vitro and was expected to be translated into the clinic to improve the prognosis of UC.
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Tenascin-C promotes acute kidney injury to chronic kidney disease progression by impairing tubular integrity via αvβ6 integrin signaling.
Haili Zhu,Jinlin Liao,Xianke Zhou,Xue Hong,Dongyan Song,Fan Fan Hou,Youhua Liu,Youhua Liu,Haiyan Fu +8 more
TL;DR: It is demonstrated that tenascin-C is a biomarker and a mediator of kidney fibrogenesis and a pathogenic mediator that impairs tubular integrity, and blockade of the tenascIn-C/αvβ6 integrin/FAK signal cascade may be a novel strategy for therapeutic intervention of kidneys fibrosis.
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Fibroblast-Specific β-Catenin Signaling Dictates the Outcome of AKI.
Dong Zhou,Haiyan Fu,Liangxiang Xiao,Hongyan Mo,Hui Zhuo,Xiao-Jun Tian,Lin Lin,Jianhua Xing,Youhua Liu +8 more
TL;DR: It is suggested that fibroblast-specific β-catenin signaling can control tubular injury and repair in AKI by modulating HGF expression.
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Fibrillin-1–enriched microenvironment drives endothelial injury and vascular rarefaction in chronic kidney disease
Li Li,Jinlin Liao,Qian Yuan,Xue Hong,Jing Li,Yiling Peng,Meizhi He,Haili Zhu,Mingsheng Zhu,Fan Fan Hou,Haiyan Fu,Youhua Liu,Youhua Liu +12 more
TL;DR: In this article, a central role of the extracellular microenvironment in controlling endothelial cell survival and proliferation in chronic kidney disease (CKD) was shown, and it was shown that FBN1 plays a role in mediating vascular rarefaction by orchestrating a hostile microenvironment for endothelial cells.
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