Haixing Wang
Illinois Institute of Technology
6 Papers
3 Citations
Haixing Wang is an academic researcher from Illinois Institute of Technology. The author has contributed to research in topics: Chemistry & Chelation. The author has an hindex of 1, co-authored 3 publications.
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Papers
Design, Synthesis, and Biological Evaluation of Polyaminocarboxylate Ligand-Based Theranostic Conjugates for Antibody-Targeted Cancer Therapy and Near-Infrared Optical Imaging.
Siyuan Ren,Xiang Sun,Haixing Wang,Trung Hai Nguyen,Negar Sadeghipour,Xiaochun Xu,Chi Soo Kang,Yujie Liu,Hua Xu,Ningjie Wu,Yanda Chen,Kenneth M. Tichauer,David D. L. Minh,Hyun-Soon Chong +13 more
TL;DR: The therapeutic conjugate was capable of significantly inhibiting tumor growth, leading to nearly complete disappearance of tumors in the mice, and the novel ligand‐based therapeutic and theranostic conjugates for targeted iron chelation cancer therapy and imaging applications support further evaluation.
New Bifunctional Chelator 3p-C-NEPA for Potential Applications in Lu(III) and Y(III) Radionuclide Therapy and Imaging.
Xiang Sun,Chi Soo Kang,Inseok Sin,Shuyuan Zhang,Siyuan Ren,Haixing Wang,Dijie Liu,Michael R. Lewis,Hyun-Soon Chong +8 more
- 28 Oct 2020
TL;DR: A scorpion-like chelator is proposed to completely saturate the coordination spheres of Y( III) and Lu(III) to generate efficient bifunctional chelators for targeted radionuclide therapy and imaging of various diseases.
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Pyridine-containing octadentate ligand NE3TA-PY for formation of neutral complex with 177Lu(III) and 90Y(III) for radiopharmaceutical applications: Synthesis, DFT calculation, radiolabeling, and in vitro complex stability
TL;DR: In this paper, the pyridine-containing polyaminocarboxylate ligand NE3TA-PY (7]-2-[(carboxymethyl)(2-pyridylmethyl)amino]ethyl]-1, 4,7-triazacyclonononane-1,4-diacetic acid) was designed for targeted radionuclide therapy applications.
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Synthesis and evaluation of a novel bifunctional ligand 3o-C-NETA for Yttrium-90 and Lutetium-177.
Hua Xu,Pengfei Dong,Haixing Wang,Inseok Sin,Siyuan Ren,Xiang Sun,Hyun-Soon Chong +6 more
Novel Chelating Agents for Zirconium-89-Positron Emission Tomography (PET) Imaging: Synthesis, DFT Calculation, Radiolabeling, and In Vitro and In Vivo Complex Stability
Chi Soo Kang,Shuyuan Zhang,Haixing Wang,Yujie Liu,Siyuan Ren,Yanda Chen,Jingbai Li,Nilantha Bandara,Andrey Yu. Rogachev,Buck E. Rogers,Hyun-Soon Chong +10 more
TL;DR: The synthesis and evaluation of novel chelating agents for zirconium-89 (89Zr) with positron emission tomography (PET) imaging applications are reported and NODHA was found to form stronger bonds with Zr(IV) when compared to NOTHA and N ODHA-PY, and NodHA-NODHA showed the highest stability in human serum without losing 89Zr.