Haisu Yi
Sun Yat-sen University
5 Papers
1 Citations
Haisu Yi is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications.
Chat about Author
Papers
Quantitative Analysis of the Bacteria in Blepharitis With Demodex Infestation.
TL;DR: The results suggest that D. folliculorum and P. acnes have a role in the occurrence of the chronic blepharitis, and further studies are required to reveal the relationship between these two organisms in blePharitis.
A Class of Shark‐Derived Single‐Domain Antibodies can Broadly Neutralize SARS‐Related Coronaviruses and the Structural Basis of Neutralization and Omicron Escape
Bo Feng,Zhilong Chen,Jing Sun,Tingting Xu,Qian Wang,Haisu Yi,Xuefeng Niu,Jiabin Zhu,Mengzhu Fan,Rui-tian Hou,Ying Shao,Sihui Huang,Cuiyun Li,Peiyu Hu,Pingqian Zheng,Ping He,Jia Luo,Qihong Yan,Xiaoli Xiong,Jinsong Liu,Jincun Zhao,Ling Chen +21 more
TL;DR: It is found that the S375F mutation on Omicron RBD disrupts the structure of β‐strand, thus impair the binding with 20G6, and demonstrates that shark‐derived vnarbodies offer a prophylactic and therapeutic option against most SARS‐CoV‐2 variants and provide insights into antibody evasion by the OmicRON variant.
20
Seroprevalence of neutralizing antibodies against adenovirus type 26 and 35 in healthy populations from Guangdong and Shandong provinces, China
Haisu Yi,Qian Wang,Jiankai Deng,Hengchun Li,Yingkun Zhang,Zhilong Chen,Tianxing Ji,Wenming Liu,Xuehua Zheng,Qing Ma,Xinxin Sun,Yudi Zhang,Xuegao Yu,Mengzhang He,Ling Chen,Ying Feng +15 more
TL;DR: Zhang et al. as discussed by the authors established micro-neutralizing assays to investigate the seroprevalence of neutralizing antibodies (nAbs) against human adenovirus type 26 and type 35 (HAdV35) in the general population of Guangdong and Shandong provinces, China.
5
Broad and durable antibody response after vaccination with inactivated SARS-CoV-2 in individuals with a history of 2003 SARS-CoV infection
Huan Liang,Peiyan Zheng,Qian Wang,Yijun Deng,D. Liang,Haisu Yi,Yuanyi Cheng,Xinwei Zhao,Jing Ma,Yidong Yang,Peiyu Hu,Pingqian Zheng,Yudi Zhang,Shuangshuang Huang,Xia Lin,Changwen Ke,Xuefeng Niu,Baoqing Sun,Lingdan Chen +18 more
TL;DR: Findings suggested a great possibility of developing a universal vaccine by heterologous vaccination using spike antigens from different SARS-related coronaviruses as well as neutralizing activities measured by authentic viruses and pseudoviruses.
2
SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope
Ping He,Banghui Liu,Xijie Gao,Qihong Yan,Rongjuan Pei,Jing Sun,Qiu Yan Chen,Rui-tian Hou,Zimu Li,Yanjun Zhang,Jincun Zhao,Hao Sun,Bo Feng,Qian Wang,Haisu Yi,Peiyu Hu,Pingchao Li,Yudi Zhang,Zhilong Chen,Xuefeng Niu,Xiaolin Zhong,Liang Jin,Xiaofeng Liu,Kun Qu,Katarzyna A. Ciazynska,Andrew P. Carter,John A. G. Briggs,Jizheng Chen,Jinsong Liu,Xinwen Chen,Jun He,Ling Chen,Xiaoli Xiong +32 more
TL;DR: In this paper , a representative antibody R1-32 from a lineage of VH1-69 germline antibodies was isolated by cryo-EM and showed that it targets a semi-cryptic epitope in the spike receptor-binding domain.