Haiming Jiang
Guangzhou Medical University
27 Papers
62 Citations
Haiming Jiang is an academic researcher from Guangzhou Medical University. The author has contributed to research in topics: Virus & Medicine. The author has an hindex of 8, co-authored 21 publications.
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Papers
Liu Shen capsule shows antiviral and anti-inflammatory abilities against novel coronavirus SARS-CoV-2 via suppression of NF-κB signaling pathway.
Qinhai Ma,Weiqi Pan,Run-Feng Li,Bin Liu,Chufang Li,Yuqi Xie,Zhoulang Wang,Jin Zhao,Haiming Jiang,Jicheng Huang,Yongxia Shi,Jun Dai,Kui Zheng,Xiaobo Li,Zifeng Yang +14 more
TL;DR: Findings indicate that LS could inhibit SARS-CoV-2 virus infection via downregulating the expression of inflammatory cytokines induced virus and regulating the activity of NF-κB/MAPK signaling pathway in vitro, making its promising candidate treatment for controlling COVID-19 disease.
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Identification of natural compounds as SARS-CoV-2 entry inhibitors by molecular docking-based virtual screening with bio-layer interferometry.
Dingqi Zhang,Sami Hamdoun,Ruihong Chen,Li Jun Yang,Chi Kio Ip,Yuan-Qing Qu,Run-Feng Li,Haiming Jiang,Zifeng Yang,Sookja Kim Chung,Liang Liu,Vincent Kam Wai Wong +11 more
TL;DR: In this paper, the identification of natural compounds as potential SARS-CoV-2 entry inhibitors using the molecular docking-based virtual screening coupled with bilayer interferometry (BLI) was reported.
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β-sitosterol ameliorates influenza A virus-induced proinflammatory response and acute lung injury in mice by disrupting the cross-talk between RIG-I and IFN/STAT signaling.
Beixian Zhou,Jing Li,Xiaoli Liang,Xiping Pan,Yanbing Hao,Peifang Xie,Haiming Jiang,Zifeng Yang,Zifeng Yang,Nanshan Zhong,Nanshan Zhong +10 more
TL;DR: It is demonstrated that β-sitosterol dose-dependently suppresses inflammatory response through NF-κB and p38 mitogen-activated protein kinase (MAPK) signaling in influenza A virus-infected cells and protects mice from lethal IAV infection.
Inhibition of the infectivity and inflammatory response of influenza virus by Arbidol hydrochloride in vitro and in vivo (mice and ferret).
Yutao Wang,Yuewen Ding,Chunguang Yang,Runfeng Li,Qiuling Du,Yanbing Hao,Li Zhengtu,Haiming Jiang,Jin Zhao,Qiaoyan Chen,Zifeng Yang,Zifeng Yang,Zhanlong He +12 more
TL;DR: The results clarified the activity of ARB in both suppressing virus propagation and modulating the expression of inflammatory cytokines in vitro and in vivo, it can be as an effective drug to treat the influenza virus infection.
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Imidazole-based pinanamine derivatives: Discovery of dual inhibitors of the wild-type and drug-resistant mutant of the influenza A virus.
Jianghong Dong,Shengwei Chen,Runfeng Li,Wei Cui,Haiming Jiang,Yixia Ling,Zifeng Yang,Wenhui Hu +7 more
TL;DR: In this article, a structure-activity relationship study of a series of imidazole-linked pinanamine derivatives was conducted by modifying the imidaze ring of this compound, which was identified as being active on an amantadine-sensitive virus through blocking of the viral M2 ion channel.
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