Haig H. Kazazian
Johns Hopkins University School of Medicine
319 Papers
4.2K Citations
Haig H. Kazazian is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Gene & Retrotransposon. The author has an hindex of 98, co-authored 315 publications. Previous affiliations of Haig H. Kazazian include University of Pennsylvania & Post Graduate Institute of Medical Education and Research.
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Papers
Adult hemoglobin synthesis in the human fetus.
TL;DR: Information is presented on the time of onset of @-chain synthesis and the synthesis of abnormal @ chains in the fetus and the techniques used, including separation of hemoglobin by Biorex 70 column chromatography and separation of globin chains on cellulose acetate gel electrophoresis.
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Isolation and characterization of the translation product of a β‐globin gene nonsense mutation (β121 GAA→TAA)
TL;DR: The results may explain the phenotype of inclusion body β‐thalassaemia in heterozygotes, which is atypical of heterozygous β°‐thalASSaemia.
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Intrinsic potential for high fetal hemoglobin production in a Druze family with β-thalassemia is due to an unlinked genetic determinant
Ariella Oppenheim,Avi Yaari,Deborah Rund,Eliezer A. Rachmilewitz,David G. Nathan,Corinne Wong,Haig H. Kazazian,Barbara A. Miller +7 more
TL;DR: A young niece of the propositus with β°-thalassemia major was recently discovered, who was homozygous for the same β-globin allele and haplotype as the propos Titus, suggesting that the genetic determinant for increased γ-gene expression in the propositis is unlinked to the β- globin gene cluster.
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