Hae Young Chung
Pusan National University
579 Papers
3.2K Citations
Hae Young Chung is an academic researcher from Pusan National University. The author has contributed to research in topics: Chemistry & Oxidative stress. The author has an hindex of 72, co-authored 529 publications. Previous affiliations of Hae Young Chung include Johns Hopkins University School of Medicine & New Generation University College.
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Papers
The redox-sensitive DNA binding sites responsible for age-related downregulation of SMP30 by ERK pathway and reversal by calorie restriction.
TL;DR: The data strongly indicate that the SMP30 transcriptional process is redox-sensitive and its modulation occurs at DNA binding sites 3 and 5 in the promoter region, and that the downregulation of S MP30 is likely involved in ERK signal pathway.
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Erratum to: Differential effects of enalapril and losartan on body composition and indices of muscle quality in aged male Fischer 344 x Brown Norway rats (Age DOI: 10.1007/s11357-010-9196-y)
Age-related change in γH2AX of Drosophila muscle: its significance as a marker for muscle damage and longevity
Ho-Jun Jeon,Young-Shin Kim,Joung Sun Park,Jung Hoon Pyo,Hyun Jin Na,In Joo Kim,Cheol Min Kim,Hae Young Chung,Nam Deuk Kim,Robert Arking,Mi-Ae Yoo +10 more
TL;DR: Age-related changes of γH2AX, an indicator of DNA strand breaks, in adult Drosophila muscle are investigated to document whether its changes are correlated with muscle degeneration and lifespan, and indicate that γ H2AX may be a reliable biomarker for assessing muscle aging in Dosophila.
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Evaluation of Antimelanogenic Activity and Mechanism of Galangin in Silico and in Vivo
Ki Wung Chung,Hyeong Oh Jeong,Eun Kyeong Lee,Su Jeong Kim,Pusoon Chun,Hae Young Chung,Hyung Ryong Moon +6 more
TL;DR: Data indicates that galangin shows strong tyrosinase inhibition activity, which suggests that it may be an effective skin-whitening agent.
MHY-449, a novel dihydrobenzofuro[4,5-b][1,8] naphthyridin-6-one derivative, induces apoptotic cell death through modulation of Akt/FoxO1 and ERK signaling in PC3 human prostate cancer cells
Sun Hwa Lee,Yong Jung Kang,Bokyung Sung,Dong Hwan Kim,Hyun Sook Lim,Hyerim Kim,Seong Jin Kim,Jeong-Hyun Yoon,Hyung Ryong Moon,Hae Young Chung,Nam Deuk Kim +10 more
TL;DR: Findings suggest that MHY-449 induces apoptosis via downregulation of the Akt/FoxO1 and activation of ERK in androgen-independent, p53-null and PTEN-negative PC3 human prostate cancer cells.