Hae-Ra Cho
University Health Network
9 Papers
7 Citations
Hae-Ra Cho is an academic researcher from University Health Network. The author has contributed to research in topics: Carcinogenesis & Lung. The author has an hindex of 4, co-authored 8 publications. Previous affiliations of Hae-Ra Cho include University of Toronto.
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Papers
XB130 promotes bronchioalveolar stem cell and Club cell proliferation in airway epithelial repair and regeneration
Hiroaki Toba,Yingchun Wang,Xiao-Hui Bai,Ricardo Zamel,Hae-Ra Cho,Hongmei Liu,Alonso Lira,Shaf Keshavjee,Shaf Keshavjee,Mingyao Liu,Mingyao Liu +10 more
TL;DR: XB130 is involved in bronchioalveolar stem cell and Club cell proliferation, likely through the PI3K/Akt/GSK-3β pathway, and an inhibitory mechanism for cell proliferation and cell cycle progression was suggested in KO mice.
XB130 Deficiency Causes Congenital Hypothyroidism in Mice due to Disorganized Apical Membrane Structure and Function of Thyrocytes.
Yingchun Wang,Hiroki Shimizu,Yun-Yan Xiang,Yun-Yan Xiang,Junichi Sugihara,Wei-Yang Lu,Xiao Hui Liao,Hae-Ra Cho,Hae-Ra Cho,Hiroaki Toba,Xiao-Hui Bai,Sylvia L. Asa,Sylvia L. Asa,Peter Arvan,Samuel Refetoff,Mingyao Liu +15 more
TL;DR: In this article, XB130 (actin filament associated with thyroid nodules) is associated with mutations that impair thyroid hormone (TH) production, resulting in growth and development defects.
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Chromosome Condensation 1-Like (Chc1L) Is a Novel Tumor Suppressor Involved in Development of Histiocyte-Rich Neoplasms.
David Spillane,Ding Yan Wang,Susan Newbigging,Youdong Wang,Chang-Xin Shi,Hae-Ra Cho,Hiroki Shimizu,Anthony O. Gramolini,Mingyao Liu,Xiao-Yan Wen +9 more
TL;DR: This study suggests that Chc1L is involved in suppression of these two histiocyte-rich neoplasms in mice and supports clinical data suggesting that CHC1L loss of function is an important step in the pathogenesis of cancers containing 13q14 deletion.
Atlas of Genetics and Cytogenetics in Oncology and Haematology
Xiao-Hui Bai,Serisha Moodley,Hae-Ra Cho,Mingyao Liu,Latner Thoracic +4 more
- 01 Jan 2014
TL;DR: A review on AFAP1L2, with data on DNA/RNA, on the protein encoded and where the gene is implicated is given in this article, where the authors also discuss the role of genes in cancer.
XB130 deficiency enhances carcinogen-induced skin tumorigenesis
Hae-Ra Cho,Hae-Ra Cho,Yingchun Wang,Xiao-Hui Bai,Yun-Yan Xiang,Christina Lu,Alexander Post,Ayman Al Habeeb,Mingyao Liu +8 more
TL;DR: It is demonstrated that XB130 acts as a tumor suppressor in carcinogen-induced skin tumorigenesis that may be mediated through inhibiting inflammation.