Hadas Tamir
Israel Institute for Biological Research
41 Papers
99 Citations
Hadas Tamir is an academic researcher from Israel Institute for Biological Research. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 12, co-authored 25 publications.
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Papers
The coding capacity of SARS-CoV-2.
Yaara Finkel,Orel Mizrahi,Aharon Nachshon,Shira Weingarten-Gabbay,Shira Weingarten-Gabbay,David Morgenstern,Yfat Yahalom-Ronen,Hadas Tamir,Hagit Achdout,Dana Stein,Ofir Israeli,Adi Beth-Din,Sharon Melamed,Shay Weiss,Tomer Israely,Nir Paran,Michal Schwartz,Noam Stern-Ginossar +17 more
TL;DR: A high-resolution map of coding regions in the SARS-CoV-2 genome enables the identification of 23 unannotated open reading frames and quantification of the expression of canonical viral open readingFrames, and it is shown that viral mRNAs are not translated more efficiently than host m RNAs; instead, virus translation dominates host translation because of the high levels of viral transcripts.
Diagnosis of Imported Monkeypox, Israel, 2018.
Noam Erez,Hagit Achdout,Elad Milrot,Yuval Schwartz,Yonit Wiener-Well,Nir Paran,Boaz Politi,Hadas Tamir,Tomer Israely,Shay Weiss,Adi Beth-Din,Ohad Shifman,Ofir Israeli,Shmuel Yitzhaki,Shmuel C. Shapira,Sharon Melamed,Eli Schwartz +16 more
TL;DR: A case of monkeypox was reported in a man who returned from Nigeria to Israel in 2018 and virus was detected in pustule swabs by transmission electron microscopy and PCR and confirmed by immunofluorescence assay, tissue culture, and ELISA.
The coding capacity of SARS-CoV-2
Yaara Finkel,Orel Mizrahi,Aharon Nachshon,Shira Weingarten-Gabbay,Shira Weingarten-Gabbay,Yfat Yahalom-Ronen,Hadas Tamir,Hagit Achdout,Sharon Melamed,Shay Weiss,Tomer Israely,Nir Paran,Michal Schwartz,Noam Stern-Ginossar +13 more
TL;DR: Overall, this work reveals the full coding capacity of SARS-CoV-2 genome, providing a rich resource, which will form the basis of future functional studies and diagnostic efforts.
SARS-CoV-2 uses a multipronged strategy to impede host protein synthesis.
Yaara Finkel,Avi Gluck,Aharon Nachshon,Roni Winkler,Tal Fisher,Batsheva Rozman,Orel Mizrahi,Yoav Lubelsky,Binyamin Zuckerman,Boris Slobodin,Yfat Yahalom-Ronen,Hadas Tamir,Igor Ulitsky,Tomer Israely,Nir Paran,Michal Schwartz,Noam Stern-Ginossar +16 more
TL;DR: In this paper, the authors show that infection leads to a global reduction in translation, but that viral transcripts are not preferentially translated, which facilitates viral takeover of the mRNA pool in infected cells.
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A single dose of recombinant VSV-∆G-spike vaccine provides protection against SARS-CoV-2 challenge.
Yfat Yahalom-Ronen,Hadas Tamir,Sharon Melamed,Boaz Politi,Ohad Shifman,Hagit Achdout,Einat B. Vitner,Ofir Israeli,Elad Milrot,Dana Stein,Inbar Cohen-Gihon,Shlomi Lazar,Hila Gutman,Itai Glinert,Lilach Cherry,Yaron Vagima,Shirley Lazar,Shay Weiss,Amir Ben-Shmuel,Roy Avraham,Reut Puni,Edith Lupu,Elad Bar-David,Assa Sittner,Noam Erez,Ran Zichel,Emanuelle Mamroud,Ohad Mazor,Haim Levy,Orly Laskar,Shmuel Yitzhaki,Shmuel C. Shapira,Anat Zvi,Adi Beth-Din,Nir Paran,Tomer Israely +35 more
TL;DR: The development of a replication competent recombinant VSV-∆G-spike vaccine, in which the glycoprotein of VSV is replaced by the spike protein of SARS-CoV-2, is shown.