7 Papers
157 Citations
H. Guillozo is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Vitamin D and neurology & Vitamin. The author has an hindex of 7, co-authored 7 publications.
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Papers
Infantile Hypercalcemia and Hypercalciuria: New Insights into a Vitamin D-Dependent Mechanism and Response to Ketoconazole Treatment
Minh Nguyen,Henri Boutignon,Eric Mallet,Agnès Linglart,H. Guillozo,Frédéric Jehan,Michèle Garabédian +6 more
TL;DR: Ketoconazole is a potentially useful and safe agent for treatment of infantile hypercalcemia and abnormal vitamin D metabolism is suggested as the mechanism, possibly involving defective up-regulation of the 24-hydroxylase by 1,25-(OH)2D3, and the klotho-FGF23 axis.
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Vitamin D-resistant rickets and type 1 diabetes in a child with compound heterozygous mutations of the vitamin D receptor (L263R and R391S): dissociated responses of the CYP-24 and rel-B promoters to 1,25-dihydroxyvitamin D3.
Minh Nguyen,Arnold d'Alesio,Jean-Marc Pascussi,Rajiv Kumar,Matthew D. Griffin,Xiangyang Dong,H. Guillozo,Marthe Rizk-Rabin,Christiane Sinding,Pierre Bougnères,Frédéric Jehan,Michèle Garabédian +11 more
TL;DR: The first association between vitamin D–resistant rickets, alopecia, and type 1 diabetes in a child with compound heterozygous mutations in the VDR gene is reported.
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Interaction of 24,25-dihydroxyvitamin D3 and parathyroid hormone on bone enzymes in vitro.
TL;DR: Results show that when compared to values found in half calvaria incubated for 24 h in control medium, the bone acid and alkaline phosphatase content is significantly higher in paired halves incubated with PTE, bPTH, vitamin A, and heparin, suggesting that 24,25-(OH)2D3 may have a specific role in bone metabolism.
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Serum concentration of 24, 25-dihydroxyvitamin D in normal children and in children with rickets.
TL;DR: Development of methods for the measurement of 24,25–(OH)2D concentration in serum should provide valuable informations for a better understanding of vitamin D metabolism in physiologic and pathologic states in children.
In vitro effects of vitamin D3 metabolites on rat calvaria cAMP content.
TL;DR: The required duration of the preincubation (over 1 h) as well as the inhibitory action of cycloheximide may suggest an involvement of protein synthesis in the vitamin D3 metabolites effects.
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