25 Papers
63 Citations
H Barr is an academic researcher from Gloucestershire Hospitals NHS Foundation Trust. The author has contributed to research in topics: Dysplasia & Medicine. The author has an hindex of 7, co-authored 24 publications.
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Papers
Improvement over time in outcomes for patients undergoing endoscopic therapy for Barrett's oesophagus-related neoplasia: 6-year experience from the first 500 patients treated in the UK patient registry
Rehan Haidry,Rehan Haidry,Mohammed A. Butt,Jason M. Dunn,Jason M. Dunn,A Gupta,Gideon Lipman,Howard Smart,Pradeep Bhandari,L Smith,Robert P. Willert,Grant Fullarton,M Di Pietro,Charles Gordon,Ian D. Penman,H Barr,Praful Patel,Neil Kapoor,J Hoare,Ravi Narayanasamy,Yeng Ang,Andrew Veitch,Krish Ragunath,Marco Novelli,Laurence Lovat,Laurence Lovat +25 more
TL;DR: Clinical outcomes for BE neoplasia have improved significantly over the past 6 years with improved lesion recognition and aggressive resection of visible lesions before RFA.
Vibrational spectroscopy for cancer diagnostics
Oliver Old,Leanne M. Fullwood,Robert A H Scott,Gavin R. Lloyd,L. M. Almond,Neil A. Shepherd,Nicholas Stone,H Barr,Catherine Kendall +8 more
TL;DR: V vibrational spectroscopy, in combination with chemometric data analysis, is a powerful and accurate technique for detecting cancerous and pre-cancerous biochemical changes both in vitro and in vivo, for a range of malignant conditions.
82
Comparing outcome of radiofrequency ablation in Barrett's with high grade dysplasia and intramucosal carcinoma: a prospective multicenter UK registry.
Rehan Haidry,Rehan Haidry,Gideon Lipman,Gideon Lipman,Matthew R. Banks,Mohammed A. Butt,Mohammed A. Butt,Vinay Sehgal,David Graham,Jason M. Dunn,A Gupta,Rami Sweis,Haroon Miah,Danielle Morris,Howard Smart,Pradeep Bhandari,Robert P. Willert,Grant Fullarton,J Morris,Massimo Di Pietro,Charles Gordon,Ian D. Penman,H Barr,Praful Patel,Philip Boger,Neil Kapoor,Brinder Mahon,J Hoare,Ravi Narayanasamy,Dermot O'Toole,Edward Cheong,Natalie C. Direkze,Yeng Ang,Andrew Veitch,Anjan Dhar,David Nyalender,Krish Ragunath,A Leahy,M Fullard,Manuel Rodriguez-Justo,Marco Novelli,Laurence Lovat,Laurence Lovat +42 more
TL;DR: Patients with IMC were more likely to have visible lesions requiring initial EMR than those with HGD, and may carry a higher risk of cancer progression in the medium term, which consolidate the approach to ensuring that these patients undergo thorough endoscopic work-up.
37
Rapid infrared mapping for highly accurate automated histology in Barrett's oesophagus.
Oliver Old,Gavin R. Lloyd,Jayakrupakar Nallala,Martin Isabelle,L. M. Almond,Neil A. Shepherd,Catherine Kendall,Angela C. Shore,H Barr,Nicholas Stone +9 more
TL;DR: High glycogen content was seen in normal squamous (NSQ) tissue, high glycoprotein content was observed in glandular BE tissue, and high DNA content in dysplasia/adenocarcinoma samples, which led to classification models based on spectral differences.
23
Multi-centre Raman spectral mapping of oesophageal cancer tissues: a study to assess system transferability
Martin Isabelle,Jennifer Dorney,A Lewis,Gavin R. Lloyd,Oliver Old,Neil A. Shepherd,Manuel Rodriguez-Justo,H Barr,Katherine Lau,I Bell,S Ohrel,Geraint M.H. Thomas,Nicholas Stone,Catherine Kendall +13 more
TL;DR: The results from this study indicate that the combined correction methods do minimize the instrument and sample quality variations within and between the instrument sites, but more tissue samples of varying pathology states and greater tissue area coverage are needed to properly assess the ability of Raman spectroscopy and system transferability algorithms over multiple instrument sites.