Guy Bormans
Katholieke Universiteit Leuven
26 Papers
93 Citations
Guy Bormans is an academic researcher from Katholieke Universiteit Leuven. The author has contributed to research in topics: Radioligand & Cannabinoid receptor. The author has an hindex of 7, co-authored 26 publications. Previous affiliations of Guy Bormans include Rega Institute for Medical Research.
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Papers
Phosphodiesterase 10A PET Tracer: Kinetic Modeling and Test-Retest Study in Human Brain
Koen Van Laere,Rawaha Ahmad,Hendra Hudyana,Kristof Dubois,Mark E. Schmidt,Sofie Celen,Guy Bormans,Michel Koole +7 more
- 01 Jan 2013
TL;DR: Kinetic modeling of 18F-JNJ-42259152 shows that PDE10A activity can be reliably quantified and simplified using a reference tissue model with the frontal cortex as reference and a 60-min acquisition period.
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Synthesis and preliminary evaluation of 18F- or 11C-labeled bicyclic nucleoside analogues as potential probes for imaging varicella-zoster virus thymidine kinase gene expression using positron emission tomography.
Satish K. Chitneni,Christophe Deroose,Jan Balzarini,Rik Gijsbers,Sofie Celen,Tjibbe de Groot,Zeger Debyser,Luc Mortelmans,and Alfons M. Verbruggen,Guy Bormans +9 more
TL;DR: Two radiolabeled bicyclic nucleoside analogues were synthesized and evaluated as PET reporter probes for varicella-zoster virus thymidine kinase (VZV-tk) gene expression imaging in brain and RP-HPLC analysis of plasma and urine samples of mice injected with [11C]-3 revealed that this tracer is very stable in vivo.
12
Patent
Radiolabelled pde10 ligands
Jose Ignacio Andres-Gil,Meri De Angelis,Guy Bormans,Sofie Celen +3 more
- 27 Oct 2010
TL;DR: In this article, a radio labelled PDE10 ligand was used for imaging and quantifying the enzyme in tissues, using positron-emission tomography (PET), and compositions comprising such compounds, processes for preparing such compounds and compositions, and the use of such compounds for imaging a tissue, cells or a host, in vitro or in vivo.
10
Patent
Necrosis avid tracer agent
Yicheng Ni,Guy Bormans,Guy Marchal,Alfons Verbruggen +3 more
- 23 Jul 2004
TL;DR: In this article, the use of phenanthro[1,10,9,8-opqra]perylene-7,14-dione derivatives, and more specifically hypericin or its derivatives, as necrosis or infarct specific agents was discussed.
10
The Relationship between Brain Receptor Occupancy and Alerting Effects in Humans Support MK-0249 and MK-3134 As Inverse Agonists at the Histamine Subtype-3 Pre-synaptic Receptor
Robert Iannone,John J. Renger,William Z. Potter,Derk-Jan Dijk,Julia Boyle,John Palcza,Baiteng Zhao,Arthur J. Bergman,Koen Van Laere,Guy Bormans,Jan de Hoon,Sandra Sanabria-Bohorquez,Terrence Hamill,Nicole Calder,Inge De Lepeleire,Pascale Van Hoydonck,Sabrina Marsilio,K. Cerchio,Ruben Declercq,Sabrina Fox-Bosetti,Ajay Verma,Luc M. Van Bortel,Eric Achten,Junshui Ma,Richard Hargreaves,Ken S. Koblan,Chodakewitz Jeffrey A,Keith Gottesdiener,Gail Murphy +28 more
- 09 Dec 2009
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