Gustavo A. Salazar
European Bioinformatics Institute
13 Papers
Gustavo A. Salazar is an academic researcher from European Bioinformatics Institute. The author has contributed to research in topics: Biology & Protein Families Database. The author has an hindex of 9, co-authored 10 publications. Previous affiliations of Gustavo A. Salazar include University of Arkansas for Medical Sciences.
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Papers
The Pfam protein families database: towards a more sustainable future
Robert D. Finn,Penelope Coggill,Ruth Y. Eberhardt,Ruth Y. Eberhardt,Sean R. Eddy,Sean R. Eddy,Jaina Mistry,Alex L. Mitchell,Simon C. Potter,Marco Punta,Marco Punta,Matloob Qureshi,Amaia Sangrador-Vegas,Gustavo A. Salazar,John Tate,John Tate,Alex Bateman +16 more
TL;DR: Pfam is now primarily based on the UniProtKB reference proteomes, with the counts of matched sequences and species reported on the website restricted to this smaller set, and the facility to view the relationship between families within a clan has been improved by the introduction of a new tool.
Pfam: The protein families database in 2021.
Jaina Mistry,Sara Chuguransky,Lowri Williams,Matloob Qureshi,Gustavo A. Salazar,Erik L. L. Sonnhammer,Silvio C. E. Tosatto,Lisanna Paladin,Shriya Raj,Lorna Richardson,Robert D. Finn,Alex Bateman +11 more
TL;DR: The Pfam database is a widely used resource for classifying protein sequences into families and domains and the reintroduced Pfam-B which provides an automatically generated supplement to Pfam and contains 136 730 novel clusters of sequences that are not yet matched by a Pfam family.
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The Pfam protein families database in 2019.
Sara El-Gebali,Jaina Mistry,Alex Bateman,Sean R. Eddy,Aurelien Luciani,Simon C. Potter,Matloob Qureshi,Lorna Richardson,Gustavo A. Salazar,Alfredo Smart,Erik L. L. Sonnhammer,Layla Hirsh,Layla Hirsh,Lisanna Paladin,Damiano Piovesan,Silvio C. E. Tosatto,Robert D. Finn +16 more
TL;DR: A significant comparison to the structural classification database that led to the creation of 825 new families based on their set of uncharacterized families (EUFs) was carried out and Pfam entries were connected to the Sequence Ontology (SO) through mapping of the Pfam type definitions to SO terms.
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The InterPro protein families and domains database: 20 years on.
Matthias Blum,Hsin-Yu Chang,Sara Chuguransky,Tiago Grego,Swaathi Kandasaamy,Alex L. Mitchell,Gift Nuka,Typhaine Paysan-Lafosse,Matloob Qureshi,Shriya Raj,Lorna Richardson,Gustavo A. Salazar,Lowri Williams,Peer Bork,Alan Bridge,Julian Gough,Daniel H. Haft,Ivica Letunic,Aron Marchler-Bauer,Huaiyu Mi,Darren A. Natale,Marco Necci,Christine A. Orengo,Arun Prasad Pandurangan,Catherine Rivoire,Christian J. A. Sigrist,Ian Sillitoe,Narmada Thanki,Paul Thomas,Silvio C. E. Tosatto,Cathy H. Wu,Alex Bateman,Robert D. Finn +32 more
TL;DR: The status of InterPro (version 81.0) in its 20th year of operation, and its associated software, is reported, including updates to database content, the release of a new website and REST API, and performance improvements in InterProScan.
InterPro in 2022
Typhaine Paysan-Lafosse,Matthias Blum,Sara Chuguransky,Tiago Daniel Pereira Grego,Beatriz Pinto,Gustavo A. Salazar,Maxwell L. Bileschi,Peer Bork,Alan Bridge,Lucy J. Colwell,Julian Gough,Daniel H. Haft,Ivica Letunic,Aron Marchler-Bauer,Huaiyu Mi,Darren A. Natale,Christine A. Orengo,Arun Prasad Pandurangan,Catherine Rivoire,Christian J. A. Sigrist,Ian Sillitoe,Narmada Thanki,Paul Thomas,Silvio C. E. Tosatto,Cathy H. Wu,Alex Bateman +25 more
TL;DR: The InterPro database as discussed by the authors provides an integrative classification of protein sequences into families, and identifies functionally important domains and conserved sites, and provides a more user friendly access to the data.