Guoping Wang
Sichuan University
12 Papers
18 Citations
Guoping Wang is an academic researcher from Sichuan University. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 7, co-authored 11 publications.
Chat about Author
Papers
Sulindac, a non-steroidal anti-inflammatory drug, mediates breast cancer inhibition as an immune modulator
TL;DR: Sulindac had substantial efficacy as a single agent against 4T1 murine breast cancer and prolonged the survival of tumor-bearing mice and in the athymic nude mice, sulindac treatment was ineffective, however, inThe results advance the understanding of the mechanisms of NSAIDs and provide insight into rational drug design or antitumor immunotherapy.
Malignant Pleural Effusion and ascites Induce Epithelial-Mesenchymal Transition and Cancer Stem-like Cell Properties via the Vascular Endothelial Growth Factor (VEGF)/Phosphatidylinositol 3-Kinase (PI3K)/Akt/Mechanistic Target of Rapamycin (mTOR) Pathway *
Tao Yin,Guoping Wang,Sisi He,Guobo Shen,Chao Su,Yan Zhang,Xiawei Wei,Tinghong Ye,Ling Li,Shengyong Yang,Dan Li,Fuchun Guo,Zeming Mo,Yang Wan,Ping Ai,Xiaojuan Zhou,Yantong Liu,Yongsheng Wang,Yuquan Wei +18 more
TL;DR: It is reported that malignant PE and ascites can induce a frequent epithelial-mesenchymal transition program and endow tumor cells with stem cell properties with high efficiency, which promotes tumor growth, chemoresistance, and immune evasion.
30
Psychotropic agent thioridazine elicits potent in vitro and in vivo anti-melanoma effects.
TL;DR: In vitro pharmacological data indicated that thioridazine inhibited melanoma cells proliferation and the in vivo anti-melanoma effect of thIORidazine was confirmed by showing that intraperitoneally injection of thioriazine remarkably retarded tumor growth and reduced tumor vasculature.
26
Paclitaxel and platinum‑based chemotherapy results in transient dyslipidemia in cancer patients
Guoping Wang,Chao Su,Tao Yin +2 more
TL;DR: It is suggested that TP chemotherapy results in transient dyslipidemia, and physicians must monitor TG levels during chemotherapy to avoid TG-associated complications.
The Multi-Purpose Tool of Tumor Immunotherapy: Gene-Engineered T Cells.
TL;DR: More and more evidences indicated that the combination of the ACT and other therapies would further enhance the anti-tumor capacity of the GE-T, which is likely to link radiation therapy, tumor vaccines, CAR-T and TCR-T.