Guoping Lu
Fudan University
18 Papers
1 Citations
Guoping Lu is an academic researcher from Fudan University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 3, co-authored 4 publications.
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Papers
Application of Full-Spectrum Rapid Clinical Genome Sequencing Improves Diagnostic Rate and Clinical Outcomes in Critically Ill Infants in the China Neonatal Genomes Project.
Bingbing Wu,Wenqing Kang,Yingyuan Wang,Deyi Zhuang,Liping Chen,Long Li,Yajie Su,Xinnian Pan,Qiufen Wei,Zezhong Tang,Yangfang Li,Jin Gao,Rui Cheng,Wei Zhou,Zhangxing Wang,Gang Qiu,Jian Wang,Lin Yang,Ping Zhang,Xuemei Zhao,Yao Wang,Mingyu Gan,Gang Li,Renchao Liu,Qi Ni,Feifan Xiao,Kai Yan,Yun Cao,Guoping Lu,Yulan Lu,Huijun Wang,Wenhao Zhou +31 more
TL;DR: In this paper, the diagnostic and clinical utility of the trio-rapid genome sequencing in critically ill infants was evaluated in 13 member hospitals of the China Neonatal Genomes Project spanning 10 provinces.
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Diagnostic Performance and Clinical Impact of Metagenomic Next-Generation Sequencing for Pediatric Infectious Diseases
Yunqian Zhu,Mingyu Gan,Meng-Meng Ge,Xinran Dong,Gangfeng Yan,Qinhua Zhou,Huiju Yu,Xiaochuan Wang,Yun-tao Cao,Guoping Lu,Bingbing Wu,Wenhao Zhou +11 more
TL;DR: In this paper , the authors performed a retrospective analysis of 1,493 mNGS samples from pediatric patients with blood, central nervous system, and lower respiratory tract infections, and evaluated the agreement of mngS compared to conventional microbiological tests (CMT) based on clinical diagnosis.
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Utilizing metagenomic next-generation sequencing for diagnosis and lung microbiome probing of pediatric pneumonia through bronchoalveolar lavage fluid in pediatric intensive care unit: results from a large real-world cohort
Huili Shen,Tingyan Liu,Mei-Hua Shen,Yi Fen Zhang,Weiming Chen,Han Koo Chen,Yi-Xue Wang,Jing Liu,Jinhao Tao,Liming He,Guoping Lu,Gangfeng Yan +11 more
TL;DR: Metagenomic next-generation sequencing is valuable in the etiological diagnosis of pneumonia, especially in fungal infections, and can reveal pulmonary microecological characteristics for pneumonia patients in PICU.
4
The application of metagenomic next-generation sequencing for Angiostrongylus eosinophilic meningitis in a pediatric patient: A case report
Jing Liu,Jinhao Tao,Weiming Chen,Tingting Wang,Xin Chen,Mei-Hua Shen,Qiuxiang Ou,Yu-Ning Zhang,Yifeng Ding,Jufang Wu,Xunjia Cheng,Guoping Lu,Gangfeng Yan +12 more
TL;DR: The use of metagenomic next-generation sequencing (mNGS) to facilitate the diagnosis and treatment of an 8-year-old boy with severe A. cantonensis infection and its application for pan-pathogen detection, as well as disease monitoring, demonstrated the advantages of mNGS for early diagnosis of AEM in pediatric patients.
The outcome of acute kidney injury substages based on urinary cystatin C in critically ill children
Jiao Chen,Zhen Jiang,Hui-Fan Huang,Mian Li,Zhenjiang Bai,Yuxian Kuai,Lin Wei,Ning Liu,Xiaozhong Li,Guoping Lu,Yanhong Li +10 more
TL;DR: In this paper , the authors explored the incidence of AKI substages based on a sensitive AKI biomarker of urinary cystatin C (uCysC), and determined whether AKI sub-subgroups were relevant with respect to outcome in critically ill children.