Guodong Li
Zhengzhou University
29 Papers
82 Citations
Guodong Li is an academic researcher from Zhengzhou University. The author has contributed to research in topics: Peptide & Peptide sequence. The author has an hindex of 6, co-authored 23 publications.
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Papers
A novel cyclic peptide targeting LAG-3 for cancer immunotherapy by activating antigen-specific CD8+ T cell responses.
Wenjie Zhai,Xiuman Zhou,Hongfei Wang,Wanqiong Li,Guanyu Chen,Xinghua Sui,Guodong Li,Yuanming Qi,Yanfeng Gao,Yanfeng Gao +9 more
TL;DR: Cyclic peptide C25 provides a rationale for targeting the immune checkpoint, by blockade of LAG-3/HLA-DR interaction in order to enhance anti-tumor immunity, and C25 may provide an alternative for cancer immunotherapy besides antibody drugs.
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A novel peptide targeting Clec9a on dendritic cell for cancer immunotherapy
Zhongyi Yan,Yahong Wu,Jiangfeng Du,Guodong Li,Shengdian Wang,Wenpeng Cao,Xiuman Zhou,Wu Chunjing,Dan Zhang,Xueli Jing,Yifan Li,Hongfei Wang,Yanfeng Gao,Yuanming Qi +13 more
TL;DR: Results suggested that peptide WH could be considered as an antigen delivery carrier targeting Clec9a+ DCs for cancer immunotherapy.
Dysfunction of the energy sensor NFE2L1 triggers uncontrollable AMPK signaling and glucose metabolism reprogramming
Lu Qiu,Qiufang Yang,Wenshan Zhao,Yadi Xing,Peng Li,Xiaowen Zhou,Haoming Ning,Ranran Shi,Shan-Shan Gou,Yalan Chen,Wenjie Zhai,Yahong Wu,Guodong Li,Zhenzhen Chen,Yonggang Ren,Yanfeng Gao,Yiguo Zhang,Yuanming Qi +17 more
TL;DR: The NFE2L1/AMPK signaling pathway delineates the mechanism underlying the Nrf1-related metabolic diseases and highlight the crosstalk between redox signaling and metabolism homeostasis as discussed by the authors .
The dual effects of a novel peptibody on angiogenesis inhibition and M2 macrophage polarization on sarcoma.
TL;DR: Findings indicate that AS16-Fc could be more effective on inhibiting tumor growth angiogenesis and tumor immune microenvironment than that of peptide AS16.
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Antitumor activity of novel chimeric peptides derived from cyclinD/CDK4 and the protein transduction domain 4
Haili Wang,Xi Chen,Yan-Ping Chen,Lei Sun,Guodong Li,Mingxia Zhai,Wenjie Zhai,Qiaozhen Kang,Yanfeng Gao,Yuanming Qi +9 more
TL;DR: These peptides could be served as novel leading compounds with potent antitumor activity and induce the G1/S phase arrest and apoptosis of cancer cells.
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