Gunkut Akar
Cornell University
4 Papers
5 Citations
Gunkut Akar is an academic researcher from Cornell University. The author has contributed to research in topics: Endothelial stem cell & Proinflammatory cytokine. The author has an hindex of 3, co-authored 4 publications.
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Papers
Solar thermal polymerase chain reaction for smartphone-assisted molecular
Matthew Mancuso,Zhengda Lu,Gunkut Akar,Ethel Cesarman,David Erickson +4 more
- 01 Jan 2014
TL;DR: In this article, the authors integrate solar heating with microfluidics to eliminate thermal cycling power requirements as well as create a simple device infrastructure for polymerase chain reaction (PCR) in settings with limited infrastructure and unreliable electricity.
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Systemic expression of Kaposi sarcoma herpesvirus (KSHV) Vflip in endothelial cells leads to a profound proinflammatory phenotype and myeloid lineage remodeling in vivo
TL;DR: These mice represent the first in vivo demonstration that vFLIP is capable of inducing vascular abnormalities and changes in host microenvironment with important implications for understanding the pathogenesis and treating KSHV-associated diseases.
Identification of a nucleoside analog active against adenosine kinase–expressing plasma cell malignancies
Utthara Nayar,Utthara Nayar,Jouliana Sadek,Jonathan Reichel,Jonathan Reichel,Denise Hernandez-Hopkins,Denise Hernandez-Hopkins,Gunkut Akar,Peter Barelli,Michelle A. Sahai,Hufeng Zhou,Jennifer Totonchy,Jennifer Totonchy,David Jayabalan,Ruben Niesvizky,Ilaria Guasparri,Duane C. Hassane,Yifang Liu,Shizuko Sei,Robert H. Shoemaker,J. David Warren,Olivier Elemento,Kenneth M. Kaye,Ethel Cesarman +23 more
TL;DR: 6-ethylthioinosine (6-ETI), a nucleoside analog with toxicity to PEL in vitro and in vivo, but not to other lymphoma cell lines tested, may fill this niche for the treatment of PEL, plasmablastic lymphoma, MM, and other ADK-expressing cancers.
Solar thermal polymerase chain reaction for smartphone-assisted molecular diagnostics.
TL;DR: It is believed that exploiting the ubiquity of solar thermal energy as demonstrated here could facilitate broad availability of nucleic acid-based diagnostics in resource-limited areas.