Gui Lu
Sun Yat-sen University
91 Papers
433 Citations
Gui Lu is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 20, co-authored 81 publications. Previous affiliations of Gui Lu include Hong Kong Polytechnic University.
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Papers
Copper-Catalyzed Remote C–H Functionalizations of Naphthylamides through a Coordinating Activation Strategy and Single-Electron-Transfer (SET) Mechanism
TL;DR: The copper-catalyzed and picolinamide-assisted remote p-C–H sulfonylation of 1-naphthylamides was realized and provided a general strategy for other p-H–H bond functionalization, such as highly selective constructions of C–O, C–Br, C-I,C–C, and C–N bonds.
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Copper-free Sandmeyer-type Reaction for the Synthesis of Sulfonyl Fluorides
TL;DR: The practicality of this method was demonstrated by the broad functional group tolerance, gram-scale synthesis, and late-stage fluorosulfonylation of natural products and pharmaceuticals and the one-pot direct synthesis of sulfonyl fluorides from aromatic amines.
85
Asymmetric synthesis of trifluoromethyl-substituted 3,3′-pyrrolidinyl-dispirooxindoles through organocatalytic 1,3-dipolar cycloaddition reactions
Wei-Jie Huang,Wei-Jie Huang,Qing Chen,Ning Lin,Xian-Wen Long,Xian-Wen Long,Wei-Gao Pan,Yan-Shi Xiong,Jiang Weng,Gui Lu +9 more
TL;DR: Under bifunctional organocatalysis by cinchona-derived squaramide catalysts, a series of potential biologically important trifluoromethylated 3,3′-pyrrolidinyl-dispirooxindoles were efficiently constructed in a highly stereoselective manner.
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Organocatalytic asymmetric Mannich-type reaction of N-sulfonylimines with isocyanoacetate leading to optically active 2-imidazoline-4-carboxylates
Zhen-Wei Zhang,Gui Lu,Miao-Miao Chen,Ning Lin,Yong‐Bo Li,Tamio Hayashi,Albert S. C. Chan,Albert S. C. Chan +7 more
TL;DR: The first asymmetric Mannich-type reaction of methyl isocyanoacetate with N-sulfonylimines catalyzed by cinchona alkaloid derivatives yielded 2-imidazolines with high diastereoselectivities and good enanti-lectivities (up to >99:1 dr and 70% ee) as discussed by the authors.
70
Highly Efficient Asymmetric Michael Reaction of Aldehydes to Nitroalkenes with Diphenylperhydroindolinol Silyl Ethers as Organocatalysts
TL;DR: The authors showed that perhydroindole derivatives can also be highly efficient organocatalysts for the asymmetric Michael reaction, exhibiting comparable or even better enantioselectivities than proline derivatives.
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