Guangming Fan
Jiangnan University
9 Papers
20 Citations
Guangming Fan is an academic researcher from Jiangnan University. The author has contributed to research in topics: Transthyretin & Downregulation and upregulation. The author has an hindex of 4, co-authored 9 publications.
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Papers
A novel transthyretin/STAT4/miR-223-3p/FBXW7 signaling pathway affects neovascularization in diabetic retinopathy.
TL;DR: A novel mechanism whereby TTR might affect neovascularization through a newly identified STAT4/miR-223-3p/FBXW7 cascade in DR is found.
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KCNQ1OT1 affects the progression of diabetic retinopathy by regulating miR-1470 and epidermal growth factor receptor.
TL;DR: The results suggested that KCNQ1OT1 could sponge miR‐1470 and further regulate EGFR in DR and there should be a negative correlation between KCNNQ 1OT1 and miR-1470.
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Preparation and characterization of copper-Brevibacterium cholesterol oxidase hybrid nanoflowers.
TL;DR: The hybrid nanoflowers dramatically enhanced the structural and thermo stability, the tolerance to biphasic mixture, and the catalytic efficiency of COD; and Cu-COD nan oflowers should be of great potential in the bioconversion of sterol derivatives.
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Transcriptome analysis identified a novel 3-LncRNA regulatory network of transthyretin attenuating glucose induced hRECs dysfunction in diabetic retinopathy
TL;DR: A 3-lncRNA regulatory network was characterized underlying TTR repressing neovascularization, and showed potential diagnostic performance in DR, including oxidative stress, inflammation signalling and autophagy.
Preparation, reconstruction, and characterization of a predicted Thermomicrobium roseum sarcosine oxidase
TL;DR: A predicted sarcosine oxidase (SOX) gene from Thermomicrobium roseum DSM 5159 was expressed, reconstructed, and characterized, and circular dichroism detection revealed the stable secondary structure of the enzyme, which was unaffected by the ligands.
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