Guanglin Wang
Soochow University (Suzhou)
5 Papers
Guanglin Wang is an academic researcher from Soochow University (Suzhou). The author has contributed to research in topics: Photothermal therapy & Tumor hypoxia. The author has an hindex of 5, co-authored 5 publications.
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Papers
Photosensitizer-crosslinked in-situ polymerization on catalase for tumor hypoxia modulation & enhanced photodynamic therapy
TL;DR: This work presents an enzyme modification strategy by in-situ polymerization with photosensitizer as the cross-linker to develop multifunctional nano-theranostics with strengthened enzymatic stability, efficient tumor passive homing, SPECT imaging capability, enhanced PDT efficacy as well as decreased immunogenicity, promising for clinical translation.
186
Radionuclide I-131 Labeled Albumin-Paclitaxel Nanoparticles for Synergistic Combined Chemo-radioisotope Therapy of Cancer.
TL;DR: A simple yet effective therapeutic agent is developed for synergistic chemo-RIT of cancer, promising for future clinic translations in cancer treatment.
92
Highly Effective Radioisotope Cancer Therapy with a Non-Therapeutic Isotope Delivered and Sensitized by Nanoscale Coordination Polymers
Yu Chao,Chao Liang,Yu Yang,Guanglin Wang,Debabrata Maiti,Longlong Tian,Fei Wang,Wei Pan,Song Wu,Kai Yang,Zhuang Liu +10 more
TL;DR: This work presents a potential concept for the realization of highly effective cancer treatment with 99mTc, a short-half-life (6.0 h) diagnostic radioisotope, which is promising for cancer RIT with enhanced efficacy and reduced side effects.
65
Bottom-Up Preparation of Uniform Ultrathin Rhenium Disulfide Nanosheets for Image-Guided Photothermal Radiotherapy
Sida Shen,Yu Chao,Ziliang Dong,Guanglin Wang,Xuan Yi,Guosheng Song,Kai Yang,Zhuang Liu,Liang Cheng +8 more
TL;DR: In this paper, a 2D transition metal dichalcogenide, rhenium disulfide (ReS2) nanosheets, with uniform sizes, strong near-infrared (NIR) light, and strong X-ray attenuation, was successfully synthesized.
Rhenium-188 Labeled Tungsten Disulfide Nanoflakes for Self-Sensitized, Near-Infrared Enhanced Radioisotope Therapy.
Yu Chao,Guanglin Wang,Chao Liang,Xuan Yi,Xiaoyan Zhong,Jingjing Liu,Min Gao,Kai Yang,Liang Cheng,Zhuang Liu +9 more
TL;DR: This work presents a new concept of applying nanotechnology in RIT, by delivering radioisotopes into tumors, self-sensitizing the irradiation-induced cell damage, and modulating the tumor hypoxia state to further enhance the therapeutic outcomes.