Gregory T. Robertson
Colorado State University
62 Papers
487 Citations
Gregory T. Robertson is an academic researcher from Colorado State University. The author has contributed to research in topics: Mycobacterium tuberculosis & Medicine. The author has an hindex of 27, co-authored 51 publications. Previous affiliations of Gregory T. Robertson include Louisiana State University & LSU Health Sciences Center Shreveport.
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Papers
Four new derivatives of the broad-host-range cloning vector pBBR1MCS, carrying different antibiotic-resistance cassettes.
Michael E. Kovach,Philip H. Elzer,D. Steven Hill,Gregory T. Robertson,Michael A. Farris,R. Martin Roop,Kenneth M. Peterson +6 more
TL;DR: In this paper, four new antibiotic-resistant derivatives of the broad-host-range (bhr) cloning vector pBBR1MCS have been constructed, which are relatively small (< 5.3 kb), possess an extended multiple cloning site (MCS), and allow direct selection of recombinant plasmid molecules in Escherichia coli via disruption of the LacZ alpha peptide.
3.4K
Genome of the bacterium Streptococcus pneumoniae strain R6.
JoAnn Hoskins,William E. Alborn,Jeffrey S. Arnold,Larry C. Blaszczak,Stanley Gene Burgett,Bradley S. DeHoff,Shawn T. Estrem,Lori Fritz,Dong-Jing Fu,Wendy Fuller,Chad D. Geringer,Raymond Gilmour,Jennifer S. Glass,Hamid Khoja,Angelika R. Kraft,Robert E. Lagace,Donald J. LeBlanc,Linda N. Lee,Elliot J. Lefkowitz,Jin Lu,Patti Matsushima,Scott M. McAhren,Margaret A. Mchenney,Kevin McLeaster,Christopher W. Mundy,Thalia I. Nicas,Franklin H. Norris,MaryJeanne O'Gara,Robert B. Peery,Gregory T. Robertson,Pamela Kay Rockey,Pei-Ming Sun,Malcolm E. Winkler,Yong Yang,Michelle Young-Bellido,Genshi Zhao,Christopher A. Zook,Richard H. Baltz,S. Richard Jaskunas,Paul Robert Rosteck,Paul L. Skatrud,John I. Glass +41 more
TL;DR: In the analysis of the genome, a large number of new uncharacterized genes predicted to encode proteins that either reside on the surface of the cell or are secreted are identified and there may be new targets for vaccine and antibiotic development.
851
Bacterial and Fungal Biofilm Infections
TL;DR: This review summarizes the existing data relating to the nature, prevalence, and treatment of biofilm-associated infections and highlights experimental approaches and therapies that are being pursued toward more effective treatments.
470
Global Transcriptional Analysis of clpP Mutations of Type 2 Streptococcus pneumoniae and Their Effects on Physiology and Virulence
TL;DR: Results indicate that ClpP-mediated proteolysis plays a complex and central role in numerous pneumococcal stress responses, development of competence, and virulence.
157
Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13
Anup Aggarwal,Maloy K. Parai,Nishant D. Shetty,Deeann Wallis,Lisa K. Woolhiser,Courtney Hastings,Noton K. Dutta,Stacy Galaviz,Ramesh C. Dhakal,Rupesh Shrestha,Shoko Wakabayashi,Chris Walpole,David A. Matthews,David M. Floyd,Paul Scullion,Jennifer Riley,Ola Epemolu,Suzanne Norval,Thomas Snavely,Gregory T. Robertson,Eric J. Rubin,Thomas R. Ioerger,F. A. Sirgel,Ruben Gerhard van der Merwe,Paul D. van Helden,Peter A. Keller,Erik C. Böttger,Petros C. Karakousis,Anne J. Lenaerts,James C. Sacchettini +29 more
TL;DR: TAM16 is a benzofuran class inhibitor of Pks13 with highly potent in vitro bactericidal activity against drug-susceptible and drug-resistant clinical isolates of M. tuberculosis, and in vivo efficacy equal to the first-line TB drug isoniazid, both as a monotherapy and in combination therapy with rifampicin.
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