Grégoire Courtine
École Polytechnique Fédérale de Lausanne
181 Papers
417 Citations
Grégoire Courtine is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Spinal cord injury & Spinal cord. The author has an hindex of 53, co-authored 154 publications. Previous affiliations of Grégoire Courtine include University of Lausanne & University Hospital of Lausanne.
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Papers
Cell type prioritization in single-cell data.
Michael A. Skinnider,Michael A. Skinnider,Jordan W. Squair,Jordan W. Squair,Jordan W. Squair,Claudia Kathe,Claudia Kathe,Mark Anderson,Mark Anderson,Matthieu Gautier,Matthieu Gautier,Kaya J.E. Matson,Marco Milano,Marco Milano,Thomas H. Hutson,Thomas H. Hutson,Quentin Barraud,Quentin Barraud,Aaron A. Phillips,Leonard J. Foster,Gioele La Manno,Ariel J. Levine,Grégoire Courtine,Grégoire Courtine +23 more
TL;DR: Augur employs a machine-learning framework to quantify the separability of perturbed and unperturbed cells within a high-dimensional space and identifies the neural circuits restoring locomotion in mice following spinal cord neurostimulation.
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Undirected compensatory plasticity contributes to neuronal dysfunction after severe spinal cord injury
Janine Beauparlant,Janine Beauparlant,Rubia van den Brand,Rubia van den Brand,Quentin Barraud,Quentin Barraud,Lucia Friedli,Lucia Friedli,Pavel Musienko,Pavel Musienko,Pavel Musienko,Volker Dietz,Grégoire Courtine,Grégoire Courtine +13 more
TL;DR: In this paper, undirected compensatory plasticity within neural systems caudal to a severe spinal cord injury contributes to the development of neuronal dysfunction in the chronic stage of the injury.
Brain-controlled modulation of spinal circuits improves recovery from spinal cord injury
Marco Bonizzato,Galyna Pidpruzhnykova,Jack DiGiovanna,Polina Shkorbatova,N. V. Pavlova,Silvestro Micera,Silvestro Micera,Grégoire Courtine,Grégoire Courtine +8 more
TL;DR: The authors show in rats that a proportional stimulation interface permits voluntary movement and augments recovery in conjunction with rehabilitation, demonstrating the relevance of brain-controlled neuromodulation therapies to augment recovery from motor disorders.
Recruitment of upper-limb motoneurons with epidural electrical stimulation of the cervical spinal cord.
Nathan Greiner,Beatrice Barra,Giuseppe Schiavone,Henri Lorach,Nicholas D. James,Sara Conti,Mélanie Kaeser,Florian Fallegger,Simon Borgognon,Simon Borgognon,Stéphanie P. Lacour,Jocelyne Bloch,Grégoire Courtine,Grégoire Courtine,Marco Capogrosso,Marco Capogrosso +15 more
TL;DR: In this article, the authors combined a computational model of the cervical spinal cord with experiments in macaque monkeys to explore the mechanisms of upper-limb motoneuron recruitment with EES and characterize the selectivity of cervical interfaces.
Neuroprosthetic baroreflex controls haemodynamics after spinal cord injury
Jordan W. Squair,Matthieu Gautier,Lois Mahe,Jan Elaine Soriano,Andreas Rowald,Arnaud Bichat,Newton Cho,Newton Cho,Mark Anderson,Nicholas D. James,Jerome Gandar,Anthony V. Incognito,Anthony V. Incognito,Giuseppe Schiavone,Zoe K. Sarafis,Achilleas Laskaratos,Kay Bartholdi,Robin Demesmaeker,Salif Komi,Charlotte Moerman,Charlotte Moerman,Bita Vaseghi,Berkeley A. Scott,Ryan E. Rosentreter,Claudia Kathe,Jimmy Ravier,Laura A. McCracken,Kang Xiaoyang,Nicolas Vachicouras,Florian Fallegger,Ileana O. Jelescu,YunLong Cheng,Qin Li,Rik Buschman,Nicolas Buse,Timothy J. Denison,Sean P. Dukelow,Rebecca Charbonneau,Ian Rigby,Steven K. Boyd,Philip J. Millar,Eduardo Martin Moraud,Eduardo Martin Moraud,Marco Capogrosso,Fabien Wagner,Fabien Wagner,Quentin Barraud,Erwan Bezard,Erwan Bezard,Stéphanie P. Lacour,Jocelyne Bloch,Grégoire Courtine,Aaron A. Phillips +52 more
TL;DR: In this paper, a neuroprosthetic baroreflex was developed to restore haemodynamic stability after spinal cord injury, which is due to the interruption of supraspinal efferent commands to sympathetic circuits located in the spinal cord.