Grant Gallagher
Glasgow Royal Infirmary
10 Papers
100 Citations
Grant Gallagher is an academic researcher from Glasgow Royal Infirmary. The author has contributed to research in topics: 5' flanking region & Haplotype. The author has an hindex of 8, co-authored 10 publications.
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Papers
Mapping of the human IL10 gene and further characterization of the 5' flanking sequence.
TL;DR: The mapping of the human IL10 gene to a discrete area of chromosome 1 is described, the definition of a potential cytokine-responsive segment 3 – 4 kilobases upstream of the transcription initiation site, and the identification of two new point mutations in the immediate promoter region with their distribution in a panel of 75 unrelated healthy individuals are described.
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Structural characterisation of the distal 5' flanking region of the human interleukin-10 gene.
TL;DR: Their sequence analysis reveals a high density of Alu-repeats within the IL-10 gene locus, including three novel, related structures which the authors term Al-IL10 (A-C), which should further the understanding of how the IL -10 gene is controlled in man and how its function may vary between individuals.
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IL-10 and its homologs: important immune mediators and emerging immunotherapeutic agents
TL;DR: This meeting was organized by the authors, and sponsored by the Medical School Charite of Humboldt University, the German Rheumatoid Research Center and the Deutsche Forschungsgemeinschaft.
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Polymorphisms in the TNF gene cluster and MHC serotypes in the West of Scotland.
TL;DR: The distribution of polymorphic elements within the tumor necrosis factor (TNF) gene cluster in 105 unrelated individuals and their relationship to class I and class II major histocompatibility complex (MHC) antigens, and to the highly polymorphic microsatellites TNFa and TNFb are determined.
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Interleukin-10 promoter polymorphism in psoriasis.
TL;DR: The data suggest that the interleukin-10 locus contributes to the heritability of psoriasis susceptibility, and patients with age-of-onset of less than 40 were more likely to have a psoriatic family background if they carried this interLEukin10.G13 allele.
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