Graham Webb
GlaxoSmithKline
2 Papers
61 Citations
Graham Webb is an academic researcher from GlaxoSmithKline. The author has an hindex of 2, co-authored 2 publications.
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Papers
Enantioselective synthesis of (S)-salmeterol via asymmetric reduction of azidoketone by Pichia angusta
TL;DR: An efficient enantioselective route to ( S )-salmeterol involving asymmetric reduction of an azidoketone intermediate to an azido alcohol by Pichia angusta is described.
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Identification and optimisation of a novel series of pyrimidine based cyclooxygenase-2 (COX-2) inhibitors. Utilisation of a biotransformation approach.
Paul John Beswick,Andrew P. Blackaby,C. Bountra,Terry Brown,Kerry Browning,Ian B. Campbell,John Andrew Corfield,Robert Gleave,Steve B. Guntrip,Richard M. Hall,Sean J. Hindley,Paul F. Lambeth,Fiona S. Lucas,Neil Mathews,Alan Naylor,Hazel Player,Helen Susanne Price,Phillip J. Sidebottom,Nicholas L. Taylor,Graham Webb,Joanne O. Wiseman +20 more
TL;DR: Traditional synthetic chemistry is complemented with a biotransformations approach which efficiently provided access to an array of key target molecules in the treatment of chronic inflammatory pain.
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