Gowramma Byran
Jagadguru Sri Shivarathreeswara University
31 Papers
11 Citations
Gowramma Byran is an academic researcher from Jagadguru Sri Shivarathreeswara University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 4, co-authored 16 publications.
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Papers
Activity of phytochemical constituents of Curcuma longa (turmeric) and Andrographis paniculata against coronavirus (COVID-19): an in silico approach
TL;DR: In silico studies have been performed to explore the binding modes of chemical constituents for natural remedies like Curcuma longa (turmeric) and Andrographis paniculata against COVID-19 (PDB ID 5R82) targeting coronavirus using Schrodinger suit 2019-4, and chemical constituents from turmeric like cyclocurcumin and curcumin may produce significant activity and be useful for further development.
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Identification of some novel oxazine substituted 9-anilinoacridines as SARS-CoV-2 inhibitors for COVID-19 by molecular docking, free energy calculation and molecular dynamics studies.
TL;DR: Some oxazine substituted 9-anilinoacridines (A1–A48) was designed by docking, MM-GBSA and molecular dynamics simulation studies for their COVID-19 inhibitory activity and in silico ADMET properties of the molecules are within the recommended values.
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Acridine as an Anti-Tumour Agent: A Critical Review
Potlapati Varakumar,K V Rajagopal,Baliwada Aparna,Kannan Raman,Gowramma Byran,Clara Mariana Gonçalves Lima,Salma Rashid,Mohammed H. Nafady,Talha Bin Emran,Sławomir Wybraniec +9 more
TL;DR: In this article , the authors summarized the current breakthroughs in the chemistry of acridines as anti-cancer agents, including new structural and biologically active acridine attributes, including 9-anilinoacridine core, which intercalates DNA, and a methyl triazene DNA-methylating moiety.
Neuroprotective approaches to halt Parkinson's disease progression
Piyong Sola,Praveen Thaggikuppe Krishnamurthy,Mamta Kumari,Gowramma Byran,H.V. Gangadharappa,Kusuma Kumari Garikapati +5 more
TL;DR: In this article , an effort has been made to discuss the various mechanisms responsible for progressive neurodegeneration (disease progression) in Parkinson's disease and also multiple strategies available for halting disease progression.
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Role of natural products towards the SARS-CoV-2: A critical review
K. Raman,K V Rajagopal,Fahadul Islam,Manish Dhawan,Saikat Mitra,Baliwada Aparna,Potlapati Varakumar,Gowramma Byran,Om P. Choudhary,Talha Bin Emran +9 more
TL;DR: In this article , the authors look at the latest research on the usage of natural products to alleviate the severity of COVID-19 and determine the activity of the natural products, act against SARS-CoV-2 to various targets like Mpro, ACE-II, papain-like, chymotrypsin-like proteases, and some antiviral targets.
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