Goro Eguchi
Kumamoto University
10 Papers
196 Citations
Goro Eguchi is an academic researcher from Kumamoto University. The author has contributed to research in topics: Lens (anatomy) & Lens placode. The author has an hindex of 8, co-authored 10 publications. Previous affiliations of Goro Eguchi include National Institute for Basic Biology, Japan.
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Papers
Pax-6 and Prox 1 expression during lens regeneration from Cynops iris and Xenopus cornea : evidence for a genetic program common to embryonic lens development
Nobuhiko Mizuno,Makoto Mochii,Takamasa S. Yamamoto,Tadashi C. Takahashi,Goro Eguchi,Tokindo S. Okada +5 more
TL;DR: The expression of two early marker genes of normal lens development, Pax-6 and Prox 1, are examined, indicating that the presence of the same genetic program operates in both embryonic lens development and lens regeneration, at least partly.
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Adult human retinal pigment epithelial cells capable of differentiating into neurons.
TL;DR: Adult human RPE cells even from old person are capable of differentiating into neurons, although the ratio of mature neurons was greater in the young than in the old cell line in this condition.
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In vitro culture system for iris-pigmented epithelial cells for molecular analysis of transdifferentiation
TL;DR: Northern blot data indicates that the up-regulation of pax-6 gene could be an important event during lens regeneration as well as during normal lens development and provides a useful opportunity for analyzing cellular and molecular mechanism involved in each step of transdifferentiation.
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Expression of crystallin genes in embryonic and regenerating newt lenses
TL;DR: The expression pattern of the crystallin genes in normal lens development fundamentally resembles that during lens regeneration, suggesting the absence of unique expression programs of crystallin gene for lens regeneration not found in ontogeny.
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Lens regeneration in Xenopus is not a mere repeat of lens development, with respect to crystallin gene expression.
TL;DR: Results reveal that lens regeneration from the inner layer of the outer cornea is not simply a repetition of embryonic lens development, when examined at the level of crystallin gene transcription.
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