Gordon Wells
South African National Bioinformatics Institute
6 Papers
4 Citations
Gordon Wells is an academic researcher from South African National Bioinformatics Institute. The author has contributed to research in topics: Population & Data collection. The author has an hindex of 3, co-authored 6 publications.
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Papers
High-depth African genomes inform human migration and health
Ananyo Choudhury,Shaun Aron,Laura R. Botigué,Dhriti Sengupta,Gerrit Botha,Taoufik Bensellak,Gordon Wells,Judit Kumuthini,Daniel Shriner,Yasmina Jaufeerally Fakim,Anisah W. Ghoorah,Eileen Dareng,Trust Odia,Oluwadamilare Falola,Ezekiel Adebiyi,Scott Hazelhurst,Gaston K. Mazandu,Oscar A. Nyangiri,Mamana Mbiyavanga,Alia Benkahla,Samar K. Kassim,Nicola Mulder,Sally N. Adebamowo,Emile R. Chimusa,Donna M. Muzny,Ginger A. Metcalf,Richard A. Gibbs,Charles N. Rotimi,Michèle Ramsay,Michèle Ramsay,Adebowale Adeyemo,Zané Lombard,Neil A. Hanchard +32 more
TL;DR: The findings refine the current understanding of continental migration, identify gene flow and the response to human disease as strong drivers of genome-level population variation, and underscore the scientific imperative for a broader characterization of the genomic diversity of African individuals to understand human ancestry and improve health.
The H3ABioNet helpdesk: an online bioinformatics resource, enhancing Africa's capacity for genomics research.
Judit Kumuthini,Lyndon Zass,Sumir Panji,Samson Pandam Salifu,Jonathan K. Kayondo,Victoria Nembaware,Mamana Mbiyavanga,Ajayi Olabode,Ali Kishk,Gordon Wells,Nicola Mulder +10 more
TL;DR: The H3ABioNet HD (H3A-HD) development is reported on, outlining its design, management, usage and evaluation framework, as well as the lessons learned through implementation.
Author Correction: High-depth African genomes inform human migration and health
Ananyo Choudhury,Shaun Aron,Laura R. Botigué,Dhriti Sengupta,Gerrit Botha,Taoufik Bensellak,Gordon Wells,Judit Kumuthini,Daniel Shriner,Yasmina Jaufeerally Fakim,Anisah W. Ghoorah,Eileen Dareng,Trust Odia,Oluwadamilare Falola,Ezekiel Adebiyi,Scott Hazelhurst,Gaston K. Mazandu,Oscar A. Nyangiri,Mamana Mbiyavanga,Alia Benkahla,Samar K. Kassim,Nicola Mulder,Sally N. Adebamowo,Emile R. Chimusa,Donna M. Muzny,Ginger A. Metcalf,Richard A. Gibbs,Charles N. Rotimi,Michèle Ramsay,Michèle Ramsay,Adebowale Adeyemo,Zané Lombard,Neil A. Hanchard +32 more
Proposed Guideline for Minimum Information Stroke Research and Clinical Data Reporting
Judit Kumuthini,Lyndon Zass,Melek Chaouch,Michael Thompson,Paul Olowoyo,Mamana Mbiyavanga,Faniyan Moyinoluwalogo,Gordon Wells,Victoria Nembaware,Nicola Mulder,Mayowa O. Owolabi,H ABioNet Consortium’s Data +11 more
TL;DR: The proposed reporting guideline can be employed for research utility and adapted for clinical utility as well, and is accompanied with an associated XML schema for REDCap implementation, to increase the user friendliness of data capturing, sharing, reporting and governance.
•Posted Content
Polygenic Risk Score in Africa Population: Progress andchallenges
Yagoub Adam,Suraju Sadeeq,Judit Kumuthini,Olabode Ajayi,Gordon Wells,Solomon Oladapo Rotimi,Olubanke Olujoke Ogunlana,Emmanuel Adetiba,E. E. J. Iweala,B. Brors,Ezekiel Adebiyi +10 more
TL;DR: In this paper, the authors reviewed the conventional polygenic risk score (PRS) analysis methods and their application to sub-saharan Africa communities and concluded that the limiting factor of applying PRS analysis to subSaharan populations is the lack of sufficient GWAS data.
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