Gonghao Wang
Georgia Institute of Technology
12 Papers
38 Citations
Gonghao Wang is an academic researcher from Georgia Institute of Technology. The author has contributed to research in topics: Cell sorting & Particle. The author has an hindex of 8, co-authored 12 publications. Previous affiliations of Gonghao Wang include University of Toronto & Georgia Tech Research Institute.
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Papers
Microfluidic cellular enrichment and separation through differences in viscoelastic deformation.
TL;DR: A microfluidic approach to separate and enrich a mixture of two cell types based on differences in cell viscoelastic behavior during repeated compressions and relaxation events is reported, showing that cell sorting has strong dependency on cell viscosity.
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Microfluidic Sorting of Cells by Viability Based on Differences in Cell Stiffness
Muhymin Islam,Hannah Brink,Syndey Blanche,Caleb DiPrete,Tom Bongiorno,Nicholas Stone,Anna Liu,Anisha Philip,Gonghao Wang,Wilbur A. Lam,Wilbur A. Lam,Alexander Alexeev,Edmund K. Waller,Todd Sulchek +13 more
TL;DR: A label-free microfluidic technique to separate live and dead cells that exploits differences in cellular stiffness can simply and efficiently obtain highly pure populations of viable cells.
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Biophysical subsets of embryonic stem cells display distinct phenotypic and morphological signatures.
Tom Bongiorno,Jeremy Gura,Priyanka Talwar,Dwight M. Chambers,Katherine M. Young,Dalia Arafat,Gonghao Wang,Emily Jackson-Holmes,Peng Qiu,Todd C. McDevitt,Todd Sulchek,Todd Sulchek,Todd Sulchek +12 more
TL;DR: The results of this study indicate that intrinsic cell mechanical properties might serve as a basis for efficient, high-throughput, and label-free isolation of pluripotent stem cells, which will facilitate a greater biological understanding of pluropotency and advance the potential of plurIPotent stem cell differentiated progeny as cell sources for tissue engineering and regenerative medicine.
Stiffness Dependent Separation of Cells in a Microfluidic Device
Gonghao Wang,Wenbin Mao,Caitlin Henegar,Alexander Alexeev,Todd Sulchek +4 more
- 20 Jun 2012
TL;DR: This paper demonstrates a new strategy to continuously and non-destructively separate cells into subpopulations of soft and stiff cells by employing the microfluidic principle to separate modified lymphoblastic cells with dissimilar mechanical stiffness in high-throughput.
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Cellular enrichment through microfluidic fractionation based on cell biomechanical properties.
TL;DR: A new microfluidic cell enrichment technology that continuously fractionates cells through differences in biomechanical properties, resulting in highly pure cellular subpopulations and enables the measurement of subtle biomechanicals differences within a single cell type is reported.