Gloria Zender
Nationwide Children's Hospital
16 Papers
19 Citations
Gloria Zender is an academic researcher from Nationwide Children's Hospital. The author has contributed to research in topics: Exome sequencing & Missense mutation. The author has an hindex of 9, co-authored 14 publications. Previous affiliations of Gloria Zender include Ohio State University & The Research Institute at Nationwide Children's Hospital.
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Papers
Rare GATA5 sequence variants identified in individuals with bicuspid aortic valve
Elizabeth M. Bonachea,Sheng-Wei Chang,Gloria Zender,Stephanie LaHaye,Stephanie LaHaye,Sara Fitzgerald-Butt,Sara Fitzgerald-Butt,Kim L. McBride,Kim L. McBride,Vidu Garg +9 more
TL;DR: The findings suggest a genotype–phenotype correlation in regards to associated CHD but not cusp fusion, and rare sequence variants in GATA5 are associated with human BAV.
A genome-wide association study of congenital cardiovascular left-sided lesions shows association with a locus on chromosome 20
Neil A. Hanchard,Shanker Swaminathan,Kristine L. Bucasas,Dieter Furthner,Susan D. Fernbach,Mahshid S. Azamian,Xueqing Wang,Mark B. Lewin,Jeffrey A. Towbin,Lisa C.A. D'Alessandro,Shaine A. Morris,William J. Dreyer,Susan W. Denfield,Nancy A. Ayres,Wayne J. Franklin,Henri Justino,M. Regina Lantin-Hermoso,Elena C. Ocampo,Alexia B. Santos,Dhaval R. Parekh,Douglas Moodie,Aamir Jeewa,Emily J. Lawrence,Hugh D. Allen,Daniel J. Penny,Charles D. Fraser,James R. Lupski,Mojisola Popoola,Lalita Wadhwa,J. David Brook,Frances A. Bu'Lock,Shoumo Bhattacharya,Seema R. Lalani,Gloria Zender,Sara Fitzgerald-Butt,Sara Fitzgerald-Butt,Jessica Bowman,Jessica Bowman,Don Corsmeier,Don Corsmeier,Peter White,Peter White,Kelsey Lecerf,Gladys Zapata,Patricia P. Hernandez,Judith A. Goodship,Vidu Garg,Vidu Garg,Bernard Keavney,Suzanne M. Leal,Heather J. Cordell,John W. Belmont,Kim L. McBride,Kim L. McBride +53 more
TL;DR: Genome-wide heritability analysis using case-control genotyped SNPs suggested that the mean heritability of LSLs attributable to common variants is moderately high, consistent with previous assertions.
Novel X-linked glomerulopathy is associated with a COL4A5 missense mutation in a non-collagenous interruption
Brian Becknell,Brian Becknell,Gloria Zender,Ronald Houston,Peter B. Baker,Kim L. McBride,Kim L. McBride,Wentian Luo,David S. Hains,David S. Hains,Dorin-Bogdan Borza,Andrew L. Schwaderer,Andrew L. Schwaderer +12 more
TL;DR: This mutation, in a non-collagenous interruption associated with severe renal disease, provides evidence for the importance of this structural motif and suggests the range of phenotypes associated with COL4A5 mutations is more diverse than previously realized.
19
•Journal Article
Abstract 12295: Utilization of Whole-Exome Sequencing to Identify Causative Mutations in Familial Congenital Heart Disease
Stephanie LaHaye,Don Corsmeier,Jessica Bowman,Sara Fitzgerald-Butt,Gloria Zender,Kevin Bosse,Kim L. McBride,Peter White,Vidu Garg +8 more
TL;DR: A large number of children with atypical heart defects are diagnosed with at least some form of CHD, but the etiology of the disease is still poorly understood.
3
Abstract 11984: A Novel Pathogenic Gata6 Variant Identified in a Family With Persistent Truncus Arteriosus, Childhood-Onset Diabetes Mellitus and Spontaneous Intestinal Perforation
Jun Yasuhara,Sathiya N. Manivannan,Uddalak Majumdar,David M Gordon,Katherine M. Myers,Gloria Zender,Kim L. McBride,Peter White,Vidu Garg +8 more
TL;DR: In this article , the authors reported a family where the father had persistent truncus arteriosus (PTA) and three children had CHD, 2 with PTA and 1 with an atrial septal defect.