Gloria Lliso-Ribera
Queen Mary University of London
9 Papers
8 Citations
Gloria Lliso-Ribera is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Synovitis & Rheumatoid arthritis. The author has an hindex of 4, co-authored 9 publications.
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Papers
Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC)
Gloria Lliso-Ribera,Frances Humby,Myles Lewis,Alessandra Nerviani,Daniele Mauro,Felice Rivellese,Stephen Kelly,Rebecca Hands,F Bene,Nandhini Ramamoorthi,Jason A. Hackney,Alberto Cauli,Ernest Choy,Andrew Filer,Peter C. Taylor,Iain B. McInnes,Michael J. Townsend,Costantino Pitzalis +17 more
TL;DR: The capacity to refine early clinical classification criteria through synovial pathobiological markers offers the potential to predict disease outcome and stratify therapeutic intervention to patients most in need.
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B cell synovitis and clinical phenotypes in rheumatoid arthritis: relationship to disease stages and drug exposure
Felice Rivellese,Frances Humby,Serena Bugatti,Liliane Fossati-Jimack,Hasan Rizvi,Davide Lucchesi,Gloria Lliso-Ribera,Alessandra Nerviani,Rebecca Hands,Giovanni Giorli,Barbara Frias,Georgina Thorborn,Edyta Jaworska,Christopher R. John,Katriona Goldmann,Myles Lewis,Antonio Manzo,Michele Bombardieri,Costantino Pitzalis,Peac-R Ra Investigators +19 more
TL;DR: The relationship of synovial B cells to clinical phenotypes at different stages of disease evolution and drug exposure in rheumatoid arthritis (RA) is defined.
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Circulating and Synovial Pentraxin-3 (PTX3) Expression Levels Correlate With Rheumatoid Arthritis Severity and Tissue Infiltration Independently of Conventional Treatments Response.
Marie-Astrid Boutet,Marie-Astrid Boutet,Alessandra Nerviani,Gloria Lliso-Ribera,Roberto Leone,Marina Sironi,Rebecca Hands,Felice Rivellese,Annalisa Del Prete,Katriona Goldmann,Myles Lewis,Alberto Mantovani,Alberto Mantovani,Barbara Bottazzi,Costantino Pitzalis +14 more
TL;DR: In this paper, the relationship between PTX3 systemic and synovial levels and the clinical features of rheumatoid arthritis (RA) in a cohort of early, treatment-naïve patients and explore the relevance of PTX-3 expression in predicting response to conventional-synthetic (cs) Disease-Modifying-Anti-Rheumatic-Drugs (DMARDs) treatment.
OP0040 Synovial cell infiltration in acpa-ve patients displays similar signatures to other seronegative inflammatory arthritis. results from the pathobiology of early arthritis cohort (PEAC)
Gloria Lliso-Ribera,Frances Humby,Alessandra Nerviani,Marie-Astrid Boutet,Stephen Kelly,Michele Bombardieri,Myles Lewis,Rebecca Hands,V. Rocher,F Bene,Christopher D. Buckley,Peter C. Taylor,Iain B. McInnes,C. Pitzalis +13 more
TL;DR: This study examines in a cohort of therapy naïve, early inflammatory arthritis patients whether ACPA-ve RA can be defined at disease initiation according to synovial pathobiological signatures and suggests shared pathophysiological mechanisms between PsA and ACPA -ve RA and support a role for future refinement of diagnosis.
THU0100 In early inflammatory arthritis a lymphoid pathotype signficantly associates with requirement for biologic therapy at 12 months follow up: results from the pathobiology of early arthritis cohort (PEAC)
Gloria Lliso-Ribera,Frances Humby,S Kelly,Michele Bombardieri,Myles Lewis,Rebecca Hands,V. Rocher,F Bene,Alessandra Nerviani,C Buckely,Peter C. Taylor,Iain B. McInnes,C. Pitzalis +12 more
TL;DR: Results demonstrate that in an early inflammatory arthritis cohort a lymphoid pathotype significantly associates with higher disease activity at baseline, sero positivity for RF and ACPA and a requirement for more aggressive therapy at 12 month, and suggests a role as a prognostic biomarker facilitating early stratification of aggressive therapeutic intervention.
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