Gilles J. Guillemin
Macquarie University
378 Papers
1K Citations
Gilles J. Guillemin is an academic researcher from Macquarie University. The author has contributed to research in topics: Kynurenine pathway & Quinolinic acid. The author has an hindex of 70, co-authored 341 publications. Previous affiliations of Gilles J. Guillemin include Sultan Qaboos University & Australian School of Advanced Medicine.
Chat about Author
Papers
BMAA and Neurodegenerative Illness.
TL;DR: A brief overview of BMAA studies is provided and an introduction to this collection of scientific manuscripts in this special issue on BMAA is provided.
Genetic Analysis of Tryptophan Metabolism Genes in Sporadic Amyotrophic Lateral Sclerosis.
Jennifer A. Fifita,Sandrine Chan Moi Fat,Emily P. McCann,Kelly L. Williams,Natalie A. Twine,Denis C. Bauer,Dominic B. Rowe,Roger Pamphlett,Roger Pamphlett,Matthew C. Kiernan,Matthew C. Kiernan,Vanessa Tan,Ian P. Blair,Gilles J. Guillemin +13 more
TL;DR: In this article, the genetic contribution of 18 genes involved in TRP metabolism, including protein synthesis, serotonin synthesis and the kynurenine pathway, was determined by interrogating whole-genome sequencing data from 614 Australian sporadic ALS cases.
Use of a Recombinant Biomarker Protein DDA Library Increases DIA Coverage of Low Abundance Plasma Proteins.
Seong Beom Ahn,Karthik Shantharam Kamath,Abidali Mohamedali,Zainab Noor,Jemma X. Wu,Dana Pascovici,Subash Adhikari,Harish R. Cheruku,Gilles J. Guillemin,Matthew J. McKay,Edouard C. Nice,Mark S. Baker +11 more
TL;DR: In this paper, the authors employed a mixture of selected recombinant proteins in DDA libraries to identify (not quantify) cancerassociated low abundance plasma proteins using SWATH/DIA.
Increased 3-hydroxykynurenine serum concentrations differentiate Alzheimer's disease patients from controls.
TL;DR: The data indicate an increased production of the neurotoxic KP metabolite 3-HK in AD, which can cross the blood–brain barrier via an active transport process and may be related to the previously reported higher production of QUIN in AD brains.
Diet rich in date palm fruits improves memory, learning and reduces beta amyloid in transgenic mouse model of Alzheimer's disease
Selvaraju Subash,Musthafa Mohamed Essa,Nady Braidy,Kathyia Awlad-Thani,Ragini Vaishnav,Samir Al-Adawi,Abdullah Al-Asmi,Gilles J. Guillemin +7 more
TL;DR: The results suggest that date fruits dietary supplementation may have beneficial effects in lowering the risk, delaying the onset or slowing down the progression of AD.