Gilbert Jay
Laboratory of Molecular Biology
2 Papers
36 Citations
Gilbert Jay is an academic researcher from Laboratory of Molecular Biology. The author has contributed to research in topics: Avian sarcoma virus & Proto-oncogene tyrosine-protein kinase Src. The author has an hindex of 2, co-authored 2 publications.
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Papers
Inhibition of the transformation-specific kinase in ASV-transformed cells by N-α-tosyl-L-lysyl chloromethyl ketone
TL;DR: The finding that the inhibition of the kinase by TLCK in vivo parallels the reversion of cell morphology to normal suggests that the Kinase has an important role in transformation and offers a biochemical rationale for treatment of tumors with this agent.
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Identification of a transformation-specific protein induced by a rous sarcoma virus
TL;DR: Pulsechase experiments indicate that this 56,000 dalton molecular weight protein is extremely unstable, with a half-life of about 20 min, and does not serve as a precursor to any of the detectable virion polypeptides.